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Literature summary for 2.1.1.296 extracted from

  • Sun, J.; Zhao, Y.; McGreal, R.; Cohen-Tayar, Y.; Rockowitz, S.; Wilczek, C.; Ashery-Padan, R.; Shechter, D.; Zheng, D.; Cvekl, A.
    Pax6 associates with H3K4-specific histone methyltransferases Mll1, Mll2, and Set1a and regulates H3K4 methylation at promoters and enhancers (2016), Epigenetics Chromatin, 9, 37 .
    View publication on PubMedView publication on EuropePMC
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Cloned(Commentary)

Cloned (Comment) Organism
gene cap2, quantitative RT-PCR expression analysis Mus musculus

Organism

Organism UniProt Comment Textmining
Mus musculus Q9CYT6
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-

Source Tissue

Source Tissue Comment Organism Textmining
alphaTN4 cell
-
 Mus musculus
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cell culture cultured lens cell Mus musculus
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lens
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 Mus musculus
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Synonyms

Synonyms Comment Organism
cap2
-
 Mus musculus

Expression

Organism Comment Expression
Mus musculus the shRNA-mediated knockdown of transcription factor Pax6 reveals downregulation of a set of direct target genes, including Cap2, Farp1, Pax6, Plekha1, Prox1, Tshz2, and Zfp536 down

General Information

General Information Comment Organism
physiological function enzyme Cap2 expression is regulated by Pax6, a key regulator of the entire cascade of ocular lens formation through specific binding to promoters and enhancers of batteries of target genes Mus musculus