Literature summary for 2.1.1.13 extracted from

Utley, C.S.; Marcell, P.D.; Allen, R.H.; Antony, A.C.; Kolhouse, J.F.
Isolation and characterization of methionine synthetase from human placenta (1985), J. Biol. Chem., 260, 13656-13665.

Search for more literature for 2.1.1.13

General Stability

General Stability	Organism
rapid loss of activity in frozen state	Homo sapiens

Molecular Weight [Da]

Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
35000	-	x * 90000 + x * 45000 + x * 35000, SDS-PAGE of reduced enzyme	Homo sapiens
45000	-	x * 90000 + x * 45000 + x * 35000, SDS-PAGE of reduced enzyme	Homo sapiens
90000	-	x * 90000 + x * 45000 + x * 35000, SDS-PAGE of reduced enzyme	Homo sapiens
160000	-	gel filtration	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Purification (Commentary)

Purification (Comment)	Organism
-	Homo sapiens

Source Tissue

Source Tissue	Comment	Organism	Textmining
placenta	-	Homo sapiens	-

Storage Stability

Storage Stability	Organism
4°C, 20% loss of activity after 2 weeks	Homo sapiens

Subunits

Subunits	Comment	Organism
?	x * 90000 + x * 45000 + x * 35000, SDS-PAGE of reduced enzyme	Homo sapiens

Turnover Number [1/s]

Turnover Number Minimum [1/s]	Turnover Number Maximum [1/s]	Substrate	Comment	Organism	Structure
additional information	-	additional information	-	Homo sapiens

Cofactor

Cofactor	Comment	Organism	Structure
vitamin B12	i.e. cobalamin, 1 mol per mol of enzyme	Homo sapiens
vitamin B12	enzyme contains a derivative of vitamin B12 as prosthetic group	Homo sapiens

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Release 2023.1 (January 2023)