Cloned (Comment) | Organism |
---|---|
expressed in Escherichia coli BL21(DE3) cells | Homo sapiens |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.005 | - |
Sulfide | with cysteine as acceptor, at pH 7.4 and 37°C | Homo sapiens | |
0.007 | - |
Sulfide | with homocysteine as acceptor, at pH 7.4 and 37°C | Homo sapiens | |
0.01 | - |
Sulfide | with glutathione as acceptor, at pH 7.4 and 37°C | Homo sapiens | |
0.13 | - |
Sulfide | with sulfite as acceptor, at pH 7.4 and 37°C | Homo sapiens | |
0.22 | - |
sulfite | at pH 7.4 and 37°C | Homo sapiens | |
0.32 | - |
Sulfide | at pH 7.4 and 37°C | Homo sapiens | |
2 | 3 | cysteine | at pH 7.4 and 37°C | Homo sapiens | |
22 | - |
glutathione | at pH 7.4 and 37°C | Homo sapiens | |
22 | - |
homocysteine | at pH 7.4 and 37°C | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
mitochondrion | - |
Homo sapiens | 5739 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | Q9Y6N5 | - |
- |
Purification (Comment) | Organism |
---|---|
Ni-NTA agarose column chromatography and Mono Q column chromatography | Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
hydrogen sulfide + cysteine + coenzyme Q1 | - |
Homo sapiens | ? | - |
? | |
hydrogen sulfide + glutathione + coenzyme Q1 | - |
Homo sapiens | S-sulfanylglutathione + reduced coenzyme Q1 | - |
? | |
hydrogen sulfide + homocysteine + coenzyme Q1 | - |
Homo sapiens | ? | - |
? | |
hydrogen sulfide + sulfide + coenzyme Q1 | - |
Homo sapiens | ? | - |
? | |
hydrogen sulfide + sulfite + coenzyme Q1 | - |
Homo sapiens | thiosulfate + reduced coenzyme Q1 | - |
? | |
additional information | no activity with DHLA, cysteamine, coenzyme A, hypotaurine, cysteine sulfinic acid, and thioredoxin | Homo sapiens | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 48000, SDS-PAGE | Homo sapiens |
Synonyms | Comment | Organism |
---|---|---|
SQR | - |
Homo sapiens |
sulfide quinone oxidoreductase | - |
Homo sapiens |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
74 | - |
Sulfide | with homocysteine as acceptor, at pH 7.4 and 37°C | Homo sapiens | |
92 | - |
Sulfide | with cysteine as acceptor, at pH 7.4 and 37°C | Homo sapiens | |
94 | - |
Sulfide | with glutathione as acceptor, at pH 7.4 and 37°C | Homo sapiens | |
113 | - |
Sulfide | with sulfite as acceptor, at pH 7.4 and 37°C | Homo sapiens | |
373 | - |
Sulfide | at pH 7.4 and 37°C | Homo sapiens |
kcat/KM Value [1/mMs-1] | kcat/KM Value Maximum [1/mMs-1] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
4.1 | - |
cysteine | at pH 7.4 and 37°C | Homo sapiens | |
4.2 | - |
homocysteine | at pH 7.4 and 37°C | Homo sapiens | |
5.1 | - |
glutathione | at pH 7.4 and 37°C | Homo sapiens | |
23.1 | - |
Sulfide | at pH 7.4 and 37°C | Homo sapiens | |
1700 | - |
sulfite | at pH 7.4 and 37°C | Homo sapiens | |
11000 | - |
Sulfide | with glutathione as acceptor, at pH 7.4 and 37°C | Homo sapiens | |
13000 | - |
Sulfide | with homocysteine as acceptor, at pH 7.4 and 37°C | Homo sapiens | |
19000 | - |
Sulfide | with cysteine as acceptor, at pH 7.4 and 37°C | Homo sapiens | |
29000 | - |
Sulfide | with sulfite as acceptor, at pH 7.4 and 37°C | Homo sapiens |