Protein Variants | Comment | Organism |
---|---|---|
C489S | mutant is incapable of reducing thioredoxin and can only be reduced to the 2-electron-state of enzyme | Drosophila melanogaster |
C489S/C490S | mutant is incapable of reducing thioredoxin and can only be reduced to the 2-electron-state of enzyme | Drosophila melanogaster |
C490S | mutant is incapable of reducing thioredoxin and can only be reduced to the 2-electron-state of enzyme | Drosophila melanogaster |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Drosophila melanogaster | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
NADPH + thioredoxin disulfide | mechanism, Cys57 attacks Cys490 in the interchange reaction between the N-terminal dithiol and the C-terminal disulfide | Drosophila melanogaster | NADP+ + thioredoxin | - |
? |
Synonyms | Comment | Organism |
---|---|---|
DmTrxR-1 | - |
Drosophila melanogaster |
thioredoxin reductase-1 | - |
Drosophila melanogaster |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADPH | - |
Drosophila melanogaster |