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Literature summary for 1.8.1.9 extracted from

  • Larsson, A.
    Thioredoxin reductase from rat liver (1973), Eur. J. Biochem., 35, 346-349.
    View publication on PubMed
Search for more literature for 1.8.1.9

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Rattus norvegicus ribonucleotide reductase, thioredoxin and thioredoxin reductase constitute a system necessary for the biosynthesis of deesoxyribonucleotides ?
-
 ?
thioredoxin + NADP+ Rattus norvegicus
-
 thioredoxin disulfide + NADPH
-
 ?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Rattus norvegicus

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Rattus norvegicus
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
-
 Rattus norvegicus
0.595
-
 purified enzyme Rattus norvegicus

Storage Stability

Storage Stability Organism
-20°C, several months Rattus norvegicus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information specific for NADPH, B side of nicotinamide ring Rattus norvegicus ?
-
 ?
additional information ribonucleotide reductase, thioredoxin and thioredoxin reductase constitute a system necessary for the biosynthesis of deesoxyribonucleotides Rattus norvegicus ?
-
 ?
thioredoxin + NADP+
-
 Rattus norvegicus thioredoxin disulfide + NADPH
-
 ?

Cofactor

Cofactor Comment Organism Structure
FAD
-
 Rattus norvegicus
NADPH specific for Rattus norvegicus