Inhibitors | Comment | Organism | Structure |
---|---|---|---|
dantrolene | non-competitive inhibition | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Purification (Comment) | Organism |
---|---|
ammonium sulfate precipitation, 2 ',5'-ADP Sepharose-4B affinity column chromatography and Sephadex G-200 gel filtration | Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
erythrocyte | - |
Homo sapiens | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
0.009 | - |
hemolysate, at 25°C, pH 8.0 | Homo sapiens |
23 | - |
2555fold purified enzyme, at 25°C, pH 8.0 | Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
glutathione disulfide + NADPH + H+ | - |
Homo sapiens | glutathione + NADP+ | - |
r |
Synonyms | Comment | Organism |
---|---|---|
glutathione reductase | - |
Homo sapiens |
glutathione: NADP+ oxidoreductase | - |
Homo sapiens |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
FAD | - |
Homo sapiens | |
NADPH | - |
Homo sapiens |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.1116 | - |
dantrolene | at 25°C, pH 8.0 | Homo sapiens |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.0523 | - |
at 25°C, pH 8.0 | Homo sapiens | dantrolene |