Literature summary for 1.8.1.17 extracted from

  • Borodina, E.; Kelly, D.P.; Schumann, P.; Rainey, F.A.; Ward-Rainey, N.L.; Wood, A.P.
    Enzymes of dimethylsulfone metabolism and the phylogenetic characterization of the facultative methylotrophs Arthrobacter sulfonivorans sp. nov., Arthrobacter methylotrophus sp. nov., and Hyphomicrobium sulfonivorans sp. nov (2002), Arch. Microbiol., 177, 173-183.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
dimethylsulfone in Hyphomicrobium strain S1, the highest activity of dimethylsulfone reductase is found after growth with dimethylsulfone Hyphomicrobium sulfonivorans

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane
-
Hyphomicrobium sulfonivorans
-
-
membrane
-
Arthrobacter methylotrophus
-
-

Organism

Organism UniProt Comment Textmining
Hyphomicrobium sulfonivorans
-
-
-
Arthrobacter methylotrophus
-
-
-
Hyphomicrobium sulfonivorans S1
-
-
-
Arthrobacter methylotrophus TGA
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
culture condition:dimethylsulfone-grown cell
-
Hyphomicrobium sulfonivorans
-
culture condition:dimethylsulfone-grown cell
-
Arthrobacter methylotrophus
-
culture condition:methylamine-grown cell
-
Hyphomicrobium sulfonivorans
-
culture condition:methylamine-grown cell
-
Arthrobacter methylotrophus
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
the specific activity of dimethylsulfone reductase in methylamine-grown bacteria is half the value seen in dimethylsulfone-grown organisms Hyphomicrobium sulfonivorans
additional information
-
the specific activity of dimethylsulfone reductase in methylamine-grown bacteria is half the value seen in dimethylsulfone-grown organisms Arthrobacter methylotrophus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
dimethyl sulfone + NADH + H+
-
Hyphomicrobium sulfonivorans dimethyl sulfoxide + H2O + NAD+
-
?
dimethyl sulfone + NADH + H+
-
Arthrobacter methylotrophus dimethyl sulfoxide + H2O + NAD+
-
?
dimethyl sulfone + NADH + H+
-
Hyphomicrobium sulfonivorans S1 dimethyl sulfoxide + H2O + NAD+
-
?
dimethyl sulfone + NADH + H+
-
Arthrobacter methylotrophus TGA dimethyl sulfoxide + H2O + NAD+
-
?

Cofactor

Cofactor Comment Organism Structure
NADH
-
Hyphomicrobium sulfonivorans
NADH
-
Arthrobacter methylotrophus

Expression

Organism Comment Expression
Hyphomicrobium sulfonivorans dimethylsulfone reductase activity is significantly lower after growth with dimethylsulfoxide or methanol down
Arthrobacter methylotrophus dimethylsulfone reductase activity is significantly lower after growth with dimethylsulfoxide or methanol down