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Literature summary for 1.6.2.2 extracted from
- NADH cytochrome b5 reductase and cytochrome b5 can act as sole electron donors to human cytochrome P450 1A1-mediated oxidation and DNA adduct formation by benzo[a]pyrene (2016), Chem. Res. Toxicol., 29, 1325-1334 .
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| NADH + ferricytochrome b5 | Rattus norvegicus | - |
NAD+ + H+ + ferrocytochrome b5 | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| NADH + ferricytochrome b5 | - |
Rattus norvegicus | NAD+ + H+ + ferrocytochrome b5 | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| CBR | - |
Rattus norvegicus |
| NADH:cytochrome b5 reductase | - |
Rattus norvegicus |
General Information
| General Information | Comment | Organism |
|---|---|---|
| metabolism | the NADH/cytochrome b5/enzyme system can act as the sole electron donor both for the first and second reduction of cytochrome P450 1A1 during the oxidation of benzo[a]pyrene in vitro | Rattus norvegicus |
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Release 2023.1 (January 2023)
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