Inhibitors | Comment | Organism | Structure |
---|---|---|---|
glutathione | inhibition of forward and reverse reaction in the presence of NADPH, no inhibition of forward reaction in the presence of NADH, 40% inhibition of reverse reaction, little or no inhibition in the absence of substrates | Bos taurus | |
glutathione disulfide | strong, time dependent inhibition of thio-NADP+ reduction by NADH and acetylpyridine adenine dinucleotide reduction by NADPH, 50% inhibition after 40 min incubation in 26.7 mM glutathione disulfide, presence of NADPH accelerates inhibition 20fold | Bos taurus | |
Phenylarsine oxide | 0.448 mM, 50% inhibition of acetylpyridine adenine dinucleotide reduction by NADPH after 1 min, 97% inhibition after 60 min, addition of glutathione restores about 50% of activity | Bos taurus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
mitochondrial membrane | - |
Bos taurus | 31966 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Bos taurus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
heart | - |
Bos taurus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
NADH + NADP+ | - |
Bos taurus | NAD+ + NADPH | - |
? | |
NADH + thio-NADP+ | - |
Bos taurus | NAD+ + thio-NADPH | - |
r | |
NADPH + oxidized 3-acetylpyridine adenine dinucleotide | - |
Bos taurus | NADP+ + reduced 3-acetylpyridine adenine dinucleotide | - |
r |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NAD+ | - |
Bos taurus | |
NADH | - |
Bos taurus | |
NADP+ | - |
Bos taurus | |
NADPH | - |
Bos taurus |