Any feedback?
Literature summary for 1.4.4.2 extracted from
- Glycine decarboxylase regulates the maintenance and induction of pluripotency via metabolic control (2019), Metab. Eng., 53, 35-47 .
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | P23378 | - |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| pluripotent stem cell | inhibition of the enzyme induces alterations of metabolome and advanced glycation end product (AGEs) accumulation, thereby suppressing the embryonic pluripotent state. Glycine decarboxylase-mediated regulation of glycolysis and controlling AGE accumulation is related to maintenance and induction of pluripotency | Homo sapiens | - |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| GLDC | - |
Homo sapiens |
| glycine decarboxylase | - |
Homo sapiens |
General Information
| General Information | Comment | Organism |
|---|---|---|
| physiological function | key enzyme in the glycine cleavage system that regulates glycolysis and methylglyoxal production in cancer | Homo sapiens |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
