BRENDA - Enzyme Database show
show all sequences of 1.3.99.6

Identification of the 37-kd rat liver protein that forms an acetaldehyde adduct in vivo as DELTA4-3-ketosteroid 5beta-reductase

Zhu, Y.; Fillienwarth, M.J.; Crabb, D.; Lumeng, L.; Lin, R.C.; Hepatology 23, 115-122 (1996)

Data extracted from this reference:

Cloned(Commentary)
Commentary
Organism
expression in Escherichia coli
Rattus norvegicus
Localization
Localization
Commentary
Organism
GeneOntology No.
Textmining
cytosol
-
Rattus norvegicus
5829
-
Molecular Weight [Da]
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
37000
-
x * 37000, SDS-PAGE
Rattus norvegicus
Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Rattus norvegicus
-
-
-
Source Tissue
Source Tissue
Commentary
Organism
Textmining
liver
of alcohol-fed animals
Rattus norvegicus
-
Subunits
Subunits
Commentary
Organism
?
x * 37000, SDS-PAGE
Rattus norvegicus
Cloned(Commentary) (protein specific)
Commentary
Organism
expression in Escherichia coli
Rattus norvegicus
Localization (protein specific)
Localization
Commentary
Organism
GeneOntology No.
Textmining
cytosol
-
Rattus norvegicus
5829
-
Molecular Weight [Da] (protein specific)
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
37000
-
x * 37000, SDS-PAGE
Rattus norvegicus
Source Tissue (protein specific)
Source Tissue
Commentary
Organism
Textmining
liver
of alcohol-fed animals
Rattus norvegicus
-
Subunits (protein specific)
Subunits
Commentary
Organism
?
x * 37000, SDS-PAGE
Rattus norvegicus
Other publictions for EC 1.3.99.6
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [C]
Temperature Range [C]
Temperature Stability [C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [C] (protein specific)
Temperature Range [C] (protein specific)
Temperature Stability [C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
676039
Sheenan
5beta-Dihydroprogesterone and ...
Homo sapiens
Mol. Hum. Reprod.
11
495-501
2005
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
5
-
-
1
-
-
-
-
-
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-
-
-
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-
-
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-
-
-
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-
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-
-
-
-
-
-
-
5
-
-
1
-
-
-
-
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-
-
-
-
-
-
-
-
-
-
655692
Lemonde
Mutations in SRD5B1 (AKR1D1), ...
Homo sapiens
Gut
52
1494-1499
2003
-
-
1
-
3
-
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1
-
2
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1
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1
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1
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3
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1
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1
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1
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391405
Ando
Expression of cholesterol 7alp ...
Rattus norvegicus
J. Lipid Res.
40
1793-1798
1999
-
-
-
-
-
-
-
-
-
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1
-
2
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2
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1
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1
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389552
Gao
Purification and properties of ...
Pseudomonas sp.
Ann. N. Y. Acad. Sci.
864
383-392
1998
-
1
-
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1
-
1
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1
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1
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1
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1
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1
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2
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1
1
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1
1
-
-
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-
-
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-
391404
Zhu
Identification of the 37-kd ra ...
Rattus norvegicus
Hepatology
23
115-122
1996
-
-
1
-
-
-
-
-
1
-
1
-
-
1
-
-
-
-
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1
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1
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1
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1
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1
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1
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1
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-
287079
Stokes
Characterization of DELTA4-3-k ...
Clostridium innocuum, Clostridium paraputrificum
Biochim. Biophys. Acta
836
255-261
1985
2
-
-
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1
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1
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2
2
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1
3
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1
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2
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2
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2
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1
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1
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2
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1
3
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1
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391381
Aries
-
Degradation of steroids by int ...
Clostridium paraputrificum
Biochim. Biophys. Acta
248
482-488
1971
-
-
-
-
-
-
5
-
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-
1
-
1
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-
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-
12
-
-
-
1
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1
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5
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1
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12
-
-
-
1
-
1
-
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391402
Davidson
Purification and mechanism of ...
Comamonas testosteroni
J. Biol. Chem.
241
906-915
1966
-
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-
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2
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1
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1
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1
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1
1
5
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1
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2
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1
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1
5
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1
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