Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | Q91ZI8 | wild-type and type 3 deiodinase knockdown mice | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
cochlea | - |
Mus musculus | - |
pup | - |
Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
3,3',5-triiodo-L-thyronine + AH2 | - |
Mus musculus | 3,3'-diiodothyronine + iodide + A + H+ | - |
? |
Synonyms | Comment | Organism |
---|---|---|
Dio3 | - |
Mus musculus |
type 3 deiodinase | - |
Mus musculus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
dithiothreitol | 50 mM | Mus musculus |
Organism | Comment | Expression |
---|---|---|
Mus musculus | decrease postnatally, persisted into adulthood at low levels | down |
Mus musculus | high expressio levels in embryos | up |
General Information | Comment | Organism |
---|---|---|
physiological function | protective role in hearing by influence of thyroid hormone, influence on cochlear development and auditory function, thyroid hormone-inactivating enzyme | Mus musculus |