Cloned (Comment) | Organism |
---|---|
recombinant enzyme expression in Rhodobacter sphaeroides strain DSM 5864, which synthesizes 5-aminolevulinic acid through the C-4 pathway and also has the genes coding for the enzymes of the C-5 pathway, except for glutamyl-tRNA reductase. Expression of the glutamyl-tRNA reductase gene from Rhodospirillum rubrum enabled the C-5 pathway in Rhodobacter sphaeroides to function upon assembling all the required genes | Rhodospirillum rubrum |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-glutamate 1-semialdehyde + NADP+ + tRNAGlu | Rhodospirillum rubrum | - |
L-glutamyl-tRNAGlu + NADPH + H+ | - |
? | |
L-glutamate 1-semialdehyde + NADP+ + tRNAGlu | Rhodospirillum rubrum DSM 467 | - |
L-glutamyl-tRNAGlu + NADPH + H+ | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rhodospirillum rubrum | - |
- |
- |
Rhodospirillum rubrum DSM 467 | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-glutamate 1-semialdehyde + NADP+ + tRNAGlu | - |
Rhodospirillum rubrum | L-glutamyl-tRNAGlu + NADPH + H+ | - |
? | |
L-glutamate 1-semialdehyde + NADP+ + tRNAGlu | - |
Rhodospirillum rubrum DSM 467 | L-glutamyl-tRNAGlu + NADPH + H+ | - |
? |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADP+ | - |
Rhodospirillum rubrum |
General Information | Comment | Organism |
---|---|---|
physiological function | the enzyme is required for the biosynthesis of 5-aminolevulinic acid | Rhodospirillum rubrum |