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Literature summary for 1.2.1.104 extracted from
- Plant pyruvate dehydrogenase complex: analysis of the kinetic properties and metabolite regulation (1978), Arch. Biochem. Biophys., 188, 70-77.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| beta-Hydroxypyruvate | competitive vs. pyruvate | Brassica oleracea |  |
| glyoxylate | noncompetitive vs. pyruvate | Brassica oleracea | |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| mitochondrion | - |
Brassica oleracea | 5739 | - |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Ca2+ | can replace Mg2+ | Brassica oleracea | |
| Mg2+ | - |
Brassica oleracea | |
| Mn2+ | can replace Mg2+ | Brassica oleracea | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Brassica oleracea | - |
var. italica, cauliflower, broccoli | - |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| floret | - |
Brassica oleracea | - |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| thiamine diphosphate | - |
Brassica oleracea | |
Ki Value [mM]
| Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.11 | - |
Hydroxypyruvate | - |
Brassica oleracea | |
| 3.27 | - |
glyoxylate | - |
Brassica oleracea | |
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Release 2023.1 (January 2023)
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