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Literature summary for 1.17.98.4 extracted from
- The hydrogenases and formate dehydrogenases of Escherichia coli (1994), Antonie van Leeuwenhoek, 66, 57-88.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| iodoacetamide | inhibition is enhanced in the presence of formate | Escherichia coli |  |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Fe | the enzyme may contain one 4Fe-4S cluster | Escherichia coli | |
| Mo | contains bis-molybdopterin guanine dinucleotide | Escherichia coli | |
| Se | selenocysteine is located at amino acid position 140 | Escherichia coli | |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| formate + HycB | Escherichia coli | the hydrogenase 3 Fe-S subunit HycB may represent the electron transfer partner of FDH-H | CO2 + reduced HycB | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Escherichia coli | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| additional information | FDH-H synthesis is optimal when Escherichia coli grows fermentatively | Escherichia coli | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| formate + benzyl viologen | FDH-H remains essentially unchanged when deuteroformate is used as a substrate | Escherichia coli | CO2 + reduced benzyl viologen | - |
? | |
| formate + HycB | the hydrogenase 3 Fe-S subunit HycB may represent the electron transfer partner of FDH-H | Escherichia coli | CO2 + reduced HycB | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| More | hydrogenase 3 (Hyd-3) together with formate dehydrogenase H (FDH-H) forms part of the formate hydrogenlyase (FHL) complex | Escherichia coli |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| Fdh-H | hydrogenase 3 (Hyd-3) together with formate dehydrogenase H (FDH-H) forms part of the formate hydrogenlyase (FHL) complex | Escherichia coli |
| formate hydrogenlyase | hydrogenase 3 (Hyd-3) together with formate dehydrogenase H (FDH-H) forms part of the formate hydrogenlyase (FHL) complex | Escherichia coli |
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