Cloned (Comment) | Organism |
---|---|
cDNA fragment corresponding to bp 278-2005 of the sequence was subcloned into a pcDNA3 vector in antisense orientation and stably transfected into SV40-WI38 lung fibroblasts cells, enzyme activity reduced in these stable cell clones, reduced protein level, reduced enzyme expression slows the rate of cell proliferation and suppresses anchorage-independent proliferation, SCD deficiency promotes apoptosis in a ceramide-independent manner | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | O00767 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
WI-38 cell | SV40-transformed human lung fibroblasts, SV40-WI38 | Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
stearic acid + AH2 + O2 | - |
Homo sapiens | oleic acid + A + H2O | - |
? |
Synonyms | Comment | Organism |
---|---|---|
SCD | - |
Homo sapiens |