Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 1.14.16.2 extracted from

  • Ekhteiari Salmas, R.; Durdagi, S.; Gulhan, M.F.; Duruyurek, M.; Abdullah, H.I.; Selamoglu, Z.
    The effects of pollen, propolis, and caffeic acid phenethyl ester on tyrosine hydroxylase activity and total RNA levels in hypertensive rats caused by nitric oxide synthase inhibition experimental, docking and molecular dynamic studies (2018), J. Biomol. Struct. Dyn., 36, 609-620 .
    View publication on PubMed

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
L-tyrosine + tetrahydrobiopterin + O2 Rattus norvegicus
-
L-dopa + 4a-hydroxytetrahydrobiopterin + H2O
-
?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus P04177
-
-

Source Tissue

Source Tissue Comment Organism Textmining
adrenal medulla
-
Rattus norvegicus
-
heart
-
Rattus norvegicus
-
hypothalamus
-
Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-tyrosine + tetrahydrobiopterin + O2
-
Rattus norvegicus L-dopa + 4a-hydroxytetrahydrobiopterin + H2O
-
?

Synonyms

Synonyms Comment Organism
tyrosine hydroxylase
-
Rattus norvegicus

Expression

Organism Comment Expression
Rattus norvegicus propolis, pollen, and caffeic acid phenethyl ester may mediate diminished enzyme activity in the heart, adrenal medulla, and hypothalamus in hypertensive rats down
Rattus norvegicus enzyme activity in the adrenal medulla, heart, and hypothalamus in Nomega-nitro-L-arginine methyl ester-treated rats is significantly increased compared to the control up