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Literature summary for 1.14.14.87 extracted from

  • Akashi, T.; Sawada, Y.; Aoki, T.; Ayabe, S.
    New scheme of the biosynthesis of formononetin involving 2,7,4'-trihydroxyisoflavanone but not daidzein as the methyl acceptor (2000), Biosci. Biotechnol. Biochem., 64, 2276-2279.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Saccharomyces cerevisiae microsomes Glycyrrhiza echinata

Organism

Organism UniProt Comment Textmining
Glycyrrhiza echinata
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(2S)-liquiritigenin + [reduced NADPH-hemoprotein reductase] + O2
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Glycyrrhiza echinata 2,7,4'-trihydroxyisoflavanone + [oxidized NADPH-hemoprotein reductase] + H2O
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?
additional information the enzyme also produces a spirodienone intermediate from (2S)-liquiritigenin which further reacts to 2,7-dihydroxy-4'-methoxyisoflavanone and formononetin Glycyrrhiza echinata ?
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?

Synonyms

Synonyms Comment Organism
2-hydroxyisoflavanone synthase
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Glycyrrhiza echinata
CYP93C2
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Glycyrrhiza echinata
IFS
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Glycyrrhiza echinata