Literature summary for 1.14.14.82 extracted from

Momose, M.; Nakayama, M.; Itoh, Y.; Umemoto, N.; Toguri, T.; Ozeki, Y.
An active hAT transposable element causing bud mutation of carnation by insertion into the flavonoid 3-hydroxylase gene (2013), Mol. Genet. Genomics, 288, 175-184.

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Protein Variants

Protein Variants	Comment	Organism
additional information	loss of enzyme activity leads to accumulation of 3,5-di-O-(beta-glucopyranosyl)pelargonidin 6''-O-4,6'''-O-1-cyclic malate instead of 3,5-di-O-(beta-glucopyranosyl)cyanidin 6''-O-4,6'''-O-1-cyclic malate, the only difference between these two anthocyanins is a hydroxyl grouppresent at the 3' position in the B-ring of aglycone. Loss of enzme results in a color change in buds from purple to deep pink. Mutation is due to an active hAT type transposable element, designated Tdic101. The color change is attributed to Tdic101 insertion into the second intron of flavonoid 3'-hydroxylase	Dianthus caryophyllus

Organism

Organism	UniProt	Comment	Textmining
Dianthus caryophyllus	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
dihydrokaempferol + [reduced NADPH-hemoprotein reductase] + O2	-	Dianthus caryophyllus	dihydroquercetin + [oxidized NADPH-hemoprotein reductase] + H2O	-	?

General Information

General Information	Comment	Organism
physiological function	loss of enzyme activity leads to accumulation of 3,5-di-O-(beta-glucopyranosyl)pelargonidin 6''-O-4,6'''-O-1-cyclic malate instead of 3,5-di-O-(beta-glucopyranosyl)cyanidin 6''-O-4,6'''-O-1-cyclic malate, the only difference between these two anthocyanins is a hydroxyl group present at the 3' position in the B-ring of aglycone. Loss of enzyme results in a color change in buds from purple to deep pink. Mutation is due to an active hAT type transposable element, designated Tdic101. The color change is attributed to Tdic101 insertion into the second intron of flavonoid 3'-hydroxylase	Dianthus caryophyllus

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Release 2023.1 (January 2023)