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Literature summary for 1.14.14.80 extracted from

  • Benveniste, I.; Tijet, N.; Adas, F.; Philipps, G.; Salan, J.; Durst, F.
    CYP86A1 from Arabidopsis thaliana encodes a cytochrome P450-dependent fatty acid omega-hydroxylase (1998), Biochem. Biophys. Res. Commun., 243, 688-693.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
expression in Saccharomyces cerevisiae Arabidopsis thaliana

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.096
-
palmitic acid 27°C, pH not specified in the publication Arabidopsis thaliana

Organism

Organism UniProt Comment Textmining
Arabidopsis thaliana P48422 isoform CYP86A1
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
lauric acid + [reduced NADPH-hemoprotein reductase] + O2 16% of the activity with palmitic acid Arabidopsis thaliana 12-hydroxylauric acid + [oxidized NADPH-hemoprotein reductase] + H2O
-
?
linoleic acid + [reduced NADPH-hemoprotein reductase] + O2 52% of the activity with palmitic acid Arabidopsis thaliana 18-hydroxylinoleic acid + [oxidized NADPH-hemoprotein reductase] + H2O
-
?
additional information isoform CYP86A1 catalyze the omega-hydroxylation of saturated and unsaturated fatty acids with chain lengths from C12 to C18 but not of hexadecane Arabidopsis thaliana ?
-
?
myristic acid + [reduced NADPH-hemoprotein reductase] + O2 49% of the activity with palmitic acid Arabidopsis thaliana 14-hydroxymyristic acid + [oxidized NADPH-hemoprotein reductase] + H2O
-
?
oleic acid + [reduced NADPH-hemoprotein reductase] + O2 61% of the activity with palmitic acid Arabidopsis thaliana 18-hydroxyoleic acid + [oxidized NADPH-hemoprotein reductase] + H2O
-
?
palmitic acid + [reduced NADPH-hemoprotein reductase] + O2
-
Arabidopsis thaliana 16-hydroxypalmitic acid + [oxidized NADPH-hemoprotein reductase] + H2O
-
?

Synonyms

Synonyms Comment Organism
CYP86A1
-
Arabidopsis thaliana
cytochrome P450 86A1
-
Arabidopsis thaliana

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
0.002
-
palmitic acid 27°C, pH not specified in the publication Arabidopsis thaliana