Activating Compound | Comment | Organism | Structure |
---|---|---|---|
Phenobarbital | maximal activity with addition of 0.5 mM phenobarbital | Panax notoginseng |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Ancymidol | 53.1% residual activity at 0.1 mM | Panax notoginseng | |
carbon monoxide | an atmosphere of 100% CO completely inhibits enzyme activity in dark. Inhibition by carbon monoxide is partially reversible upon illumination with blue light | Panax notoginseng | |
cytochrome c | 32.9% residual activity at 0.1 mM | Panax notoginseng | |
miconazole | 25.7% residual activity at 0.1 mM | Panax notoginseng | |
additional information | activity is not affected by dimethylsulfoxide at 0.1% (v/v) | Panax notoginseng |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.034 | - |
protopanaxadiol | in 100 mM phosphate buffer (pH 7.6), at 30°C | Panax notoginseng |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Panax notoginseng | very low activity with NADH | ? | - |
? | |
protopanaxadiol + [reduced NADPH-hemoprotein reductase] + O2 | Panax notoginseng | - |
protopanaxatriol + [oxidized NADPH-hemoprotein reductase] + H2O | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Panax notoginseng | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | very low activity with NADH | Panax notoginseng | ? | - |
? | |
protopanaxadiol + [reduced NADPH-hemoprotein reductase] + O2 | - |
Panax notoginseng | protopanaxatriol + [oxidized NADPH-hemoprotein reductase] + H2O | - |
? |
Synonyms | Comment | Organism |
---|---|---|
P6H | - |
Panax notoginseng |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.6 | - |
- |
Panax notoginseng |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
cytochrome P450 | - |
Panax notoginseng |
General Information | Comment | Organism |
---|---|---|
metabolism | protopanaxadiol 6-hydroxylase is a key enzyme in regulating Rg-group ginsenoside biosynthesis in Panax notoginseng cells | Panax notoginseng |