Cloned (Comment) | Organism |
---|---|
DNA and amino acid sequence determination and analysis | Catharanthus roseus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
endoplasmic reticulum | - |
Catharanthus roseus | 5783 | - |
endoplasmic reticulum membrane | T16H is anchored to the endoplasmic reticulum as a monomer via a putative 18-residue N-terminal helix | Catharanthus roseus | 5789 | - |
additional information | vindoline biosynthesis pathway enzyme subcellular localization study, overview | Catharanthus roseus | - |
- |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
tabersonine + NADPH + H+ + O2 | Catharanthus roseus | - |
16-hydroxytabersonine + NADP+ + H2O | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Catharanthus roseus | C0KYN4 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
leaf | - |
Catharanthus roseus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
tabersonine + NADPH + H+ + O2 | - |
Catharanthus roseus | 16-hydroxytabersonine + NADP+ + H2O | - |
? |
Subunits | Comment | Organism |
---|---|---|
monomer | - |
Catharanthus roseus |
Synonyms | Comment | Organism |
---|---|---|
CYP71D12 | - |
Catharanthus roseus |
T16H | - |
Catharanthus roseus |
tabersonine 16-monooxygenase | - |
Catharanthus roseus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
cytochrome P450 | - |
Catharanthus roseus |
General Information | Comment | Organism |
---|---|---|
metabolism | the enzyme catalyzes the first step in the biosynthesis of vindoline, which constitutes the main terpenoid indole alkaloid accumulated in leaves of Catharanthus roseus, spatial organization of the vindoline biosynthetic pathway, overview. Absence of metabolic channeling in the vindoline biosynthetic pathway. Importance of inter- and intracellular translocations of intermediates during the vindoline biosynthesis and potential regulatory role, overview | Catharanthus roseus |