Application | Comment | Organism |
---|---|---|
medicine | malaria decreases the activity of p-nitrophenol-hydroxylase in liver microsomes by 33%, mRNA levels are lowered compared to uninfected mice | Mus musculus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
microsome | - |
Mus musculus | - |
- |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
p-nitrophenol + NADH + H+ + O2 | Mus musculus | - |
p-nitrocatechol + NAD+ + H2O | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
male Swiss Webster mice infected by malaria pathogen Plasmodium berghei ANKA | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Mus musculus | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
0.00275 | - |
malaria infected mouse, real time kinetic method | Mus musculus |
0.00411 | - |
mouse without infection, real time kinetic method | Mus musculus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
p-nitrophenol + NADH + H+ + O2 | - |
Mus musculus | p-nitrocatechol + NAD+ + H2O | - |
? |
Synonyms | Comment | Organism |
---|---|---|
CYP2E1 | - |
Mus musculus |
p-nitrophenol-hydroxylase | - |
Mus musculus |
PNPH | - |
Mus musculus |