BRENDA - Enzyme Database
show all sequences of 1.14.13.238

Bacterial oxidation of dimethylamine, a new mono-oxygenase reaction

Eady, R.; Large, P.; Biochem. J. 111, 37P-38P (1969)

Data extracted from this reference:

Inhibitors
Inhibitors
Commentary
Organism
Structure
Dimethylamine
the enzyme is inhibited by dimethylamine concentrations above 1 mM
Aminobacter aminovorans
additional information
dimethylamine oxidation is not inhibited by semicarbazide hydrochloride
Aminobacter aminovorans
Organism
Organism
UniProt
Commentary
Textmining
Aminobacter aminovorans
-
-
-
Purification (Commentary)
Purification (Commentary)
Organism
partial purification
Aminobacter aminovorans
Source Tissue
Source Tissue
Commentary
Organism
Textmining
culture condition:dimethylamine-grown cell
-
Aminobacter aminovorans
-
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
Substrate Product ID
dimethylamine + NADPH + H+ + O2
-
741839
Aminobacter aminovorans
methylamine + formaldehyde + NADP+ + H2O
-
-
-
?
additional information
no activity with methylamine, methanol or formaldehyde. The partially purified enzyme shows no significant activity with primary, tertiary and quaternary amines, nor with sarcosine
741839
Aminobacter aminovorans
?
-
-
-
?
Synonyms
Synonyms
Commentary
Organism
dmmABC
-
Aminobacter aminovorans
pH Range
pH Minimum
pH Maximum
Commentary
Organism
5.8
7.3
-
Aminobacter aminovorans
Cofactor
Cofactor
Commentary
Organism
Structure
NADH
NADH can replace NADPH as electron donor and is slightly (1-2fold) more active
Aminobacter aminovorans
NADPH
-
Aminobacter aminovorans
Cofactor (protein specific)
Cofactor
Commentary
Organism
Structure
NADH
NADH can replace NADPH as electron donor and is slightly (1-2fold) more active
Aminobacter aminovorans
NADPH
-
Aminobacter aminovorans
Inhibitors (protein specific)
Inhibitors
Commentary
Organism
Structure
Dimethylamine
the enzyme is inhibited by dimethylamine concentrations above 1 mM
Aminobacter aminovorans
additional information
dimethylamine oxidation is not inhibited by semicarbazide hydrochloride
Aminobacter aminovorans
Purification (Commentary) (protein specific)
Commentary
Organism
partial purification
Aminobacter aminovorans
Source Tissue (protein specific)
Source Tissue
Commentary
Organism
Textmining
culture condition:dimethylamine-grown cell
-
Aminobacter aminovorans
-
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
ID
dimethylamine + NADPH + H+ + O2
-
741839
Aminobacter aminovorans
methylamine + formaldehyde + NADP+ + H2O
-
-
-
?
additional information
no activity with methylamine, methanol or formaldehyde. The partially purified enzyme shows no significant activity with primary, tertiary and quaternary amines, nor with sarcosine
741839
Aminobacter aminovorans
?
-
-
-
?
pH Range (protein specific)
pH Minimum
pH Maximum
Commentary
Organism
5.8
7.3
-
Aminobacter aminovorans
Other publictions for EC 1.14.13.238
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Synonyms
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
742712
Lidbury
Identification of dimethylami ...
Ruegeria pomeroyi
ISME J.
11
1592-1601
2017
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1
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1
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8
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1
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742736
Hawkins
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Intrasubstituent isotope effe ...
Aminobacter aminovorans
J. Am. Chem. Soc.
114
3547-3549
1992
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742819
Alberta
Spectroscopic characterizatio ...
Aminobacter aminovorans
J. Biol. Chem.
264
20467-20473
1989
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4
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1
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743014
Green
Subcellular localization and ...
Cyberlindnera jadinii, Cyberlindnera jadinii WY-3
J. Gen. Microbiol.
130
2577-2588
1984
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16
19
1
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2
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1
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23
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1
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1
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4
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4
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16
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1
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23
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1
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741840
Eady
Microbial oxidation of amines ...
Aminobacter aminovorans
Biochem. J.
125
449-459
1971
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1
9
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1
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1
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1
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9
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2
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9
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1
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9
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1
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741839
Eady
Bacterial oxidation of dimeth ...
Aminobacter aminovorans
Biochem. J.
111
37P-38P
1969
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2
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