Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
membrane | type 2 transmembrane protein. The enzyme can translocate to cell membrane from the endoplasmic reticulum membrane when it is overexpressed in cancer cell, which hydroxylate proteins such as Notch, Jagged, and cellular adhesion molecules that regulate cell migration and invasion | Homo sapiens | 16020 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | Q12797 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
paranephros | - |
Homo sapiens | - |
placenta | - |
Homo sapiens | - |
Synonyms | Comment | Organism |
---|---|---|
AAH | - |
Homo sapiens |
Organism | Comment | Expression |
---|---|---|
Homo sapiens | overexpression in many types of cancer tissues | up |
General Information | Comment | Organism |
---|---|---|
drug target | the enzyme is a potential biomarker for cancer diagnosis | Homo sapiens |
metabolism | the enzyme catalyzes the hydroxylation of specific aspartyl and asparaginyl residues in epidermal growth factor-like domains of proteins | Homo sapiens |