Any feedback?
Literature summary for 1.13.11.52 extracted from
- Properties and function of indoleamine 2,3-dioxygenase (1976), J. Biochem., 79, 13p-21p.
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 105000 | - |
enzyme from intestine, gel filtration | Oryctolagus cuniculus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Oryctolagus cuniculus | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| enzyme from intestine | Oryctolagus cuniculus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| brain | activity with D-Trp and L-Trp | Oryctolagus cuniculus | - |
| liver | liver enzyme is specific for L-Trp | Oryctolagus cuniculus | - |
| lung | activity with L-Trp and D-5-hydroxytryptophan | Oryctolagus cuniculus | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| additional information | - |
- |
Oryctolagus cuniculus |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| D-5-hydroxytryptophan + O2 | enzyme from lung | Oryctolagus cuniculus | ? | - |
? |  |
| D-Trp + O2 | enzyme from brain | Oryctolagus cuniculus | N-formyl-D-kynurenine | - |
? | |
| L-Trp + O2 | enzyme from liver is specific for L-Trp, the enzyme from brain is active with L-Trp and D-Trp, the enzyme from lung is active with L-Trp and D-5-hydroxytryptophan | Oryctolagus cuniculus | L-formylkynurenine | - |
? | |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
