Literature summary for 1.11.1.24 extracted from

Peskin, A.V.; Low, F.M.; Paton, L.N.; Maghzal, G.J.; Hampton, M.B.; Winterbourn, C.C.
The high reactivity of peroxiredoxin 2 with H(2)O(2) is not reflected in its reaction with other oxidants and thiol reagents (2007), J. Biol. Chem., 282, 11885-11892.

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Molecular Weight [Da]

Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
21805	-	1 * 21805, electrospray ionization mass spectrometry	Homo sapiens
21810	-	electrospray ionization mass spectrometry	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	P32119	-	-

Purification (Commentary)

Purification (Comment)	Organism
HiPrep 16/10 DEAE column chromatography	Homo sapiens

Source Tissue

Source Tissue	Comment	Organism	Textmining
erythrocyte	-	Homo sapiens	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
cumene hydroperoxide + reduced dithiothreitol	low activity	Homo sapiens	2-phenylpropan-2-ol + oxidized dithiothreitol	-	?
glycine chloramine + dithiothreitol	slow reaction	Homo sapiens	?	-	?
H2O2 + reduced dithiothreitol	reduced Prx2 is exceptionally reactive withH2O2 and other peroxides but shows very low reactivity with other thiol oxidants and alkylating agents	Homo sapiens	H2O + oxidized dithiothreitol	-	?
histamine chloramine + dithiothreitol	slow reaction	Homo sapiens	?	-	?
HOCl + dithiothreitol	low activity	Homo sapiens	?	-	?
monochloramine + dithiothreitol	slow reaction	Homo sapiens	?	-	?
taurine chloramine + dithiothreitol	slow reaction	Homo sapiens	?	-	?
tert-butyl hydroperoxide + reduced dithiothreitol	low activity	Homo sapiens	tert-butanol + oxidized dithiothreitol	-	?

Subunits

Subunits	Comment	Organism
monomer	1 * 21805, electrospray ionization mass spectrometry	Homo sapiens

Synonyms

Synonyms	Comment	Organism
peroxiredoxin 2	-	Homo sapiens
Prx2	-	Homo sapiens

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Release 2023.1 (January 2023)