Cloned (Comment) | Organism |
---|---|
isozyme cICDH is encoded by a single gene | Arabidopsis thaliana |
Protein Variants | Comment | Organism |
---|---|---|
additional information | introduction of an icdh mutation into the cat2 background, in which increased availability of H2O2 causes perturbed redox homeostasis and induction of stress-related genes. Accumulation of oxidized glutathione and pathogen-related responses are enhanced in double cat2 icdh mutants compared to cat2. Single icdh mutants present constitutive induction of PR genes, enhanced resistance to bacteria in icdh, cat2 and cat2 icdh is quantitatively correlated with PR gene expression. However, the effect of icdh in both Col0 and cat2 backgrounds is not associated with enhanced accumulation of salicylic acid, phenotypes, overview | Arabidopsis thaliana |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytosol | isozyme cICDH | Arabidopsis thaliana | 5829 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
isocitrate + NADP+ | Arabidopsis thaliana | - |
2-oxoglutarate + NADPH + H+ + CO2 | - |
? | |
isocitrate + NADP+ | Arabidopsis thaliana Columbia ecotype | - |
2-oxoglutarate + NADPH + H+ + CO2 | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Arabidopsis thaliana | - |
gene icdh | - |
Arabidopsis thaliana Columbia ecotype | - |
gene icdh | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
leaf | - |
Arabidopsis thaliana | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
isocitrate + NADP+ | - |
Arabidopsis thaliana | 2-oxoglutarate + NADPH + H+ + CO2 | - |
? | |
isocitrate + NADP+ | - |
Arabidopsis thaliana Columbia ecotype | 2-oxoglutarate + NADPH + H+ + CO2 | - |
? |
Synonyms | Comment | Organism |
---|---|---|
cICDH | - |
Arabidopsis thaliana |
cytosolic NADP-dependent isocitrate dehydrogenase | - |
Arabidopsis thaliana |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADP+ | - |
Arabidopsis thaliana |
General Information | Comment | Organism |
---|---|---|
physiological function | cICDH is involved in amino acid synthesis, and plays a role in redox signalling linked to pathogen responses, but cICDH is not required for plant development and primary metabolism in optimal growth conditions | Arabidopsis thaliana |