Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 1.1.1.417 extracted from

  • Lee, A.; Banta, A.; Wei, J.; Kiemle, D.; Feng, J.; Giner, J.; Welander, P.
    C-4 sterol demethylation enzymes distinguish bacterial and eukaryotic sterol synthesis (2018), Proc. Natl. Acad. Sci. USA, 115, 5884-5889.
    View publication on PubMed
Search for more literature for 1.1.1.417

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
4-desmethyllanosterol + NAD(P)+ Methylococcus capsulatus
-
 4-desmethyllanosterone + NAD(P)H + CO2 + H+
-
 ?
4-desmethyllanosterol + NAD(P)+ Methylococcus capsulatus Texas H156DRAFT2756-2755
-
 4-desmethyllanosterone + NAD(P)H + CO2 + H+
-
 ?
lanosterol + NAD(P)+ Methylococcus capsulatus
-
 lanosterone + NAD(P)H + CO2 + H+
-
 ?
lanosterol + NAD(P)+ Methylococcus capsulatus Texas H156DRAFT2756-2755
-
 lanosterone + NAD(P)H + CO2 + H+
-
 ?

Organism

Organism UniProt Comment Textmining
Methylococcus capsulatus
-
-
-
Methylococcus capsulatus Texas H156DRAFT2756-2755
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4-desmethyllanosterol + NAD(P)+
-
 Methylococcus capsulatus 4-desmethyllanosterone + NAD(P)H + CO2 + H+
-
 ?
4-desmethyllanosterol + NAD(P)+
-
 Methylococcus capsulatus Texas H156DRAFT2756-2755 4-desmethyllanosterone + NAD(P)H + CO2 + H+
-
 ?
lanosterol + NAD(P)+
-
 Methylococcus capsulatus lanosterone + NAD(P)H + CO2 + H+
-
 ?
lanosterol + NAD(P)+
-
 Methylococcus capsulatus Texas H156DRAFT2756-2755 lanosterone + NAD(P)H + CO2 + H+
-
 ?

Synonyms

Synonyms Comment Organism
sdmB
-
 Methylococcus capsulatus

Cofactor

Cofactor Comment Organism Structure
NADH
-
 Methylococcus capsulatus
NADPH
-
 Methylococcus capsulatus

General Information

General Information Comment Organism
metabolism the enzyme participates in sterol C-4 demethylation Methylococcus capsulatus