Application | Comment | Organism |
---|---|---|
medicine | 50% inhibition of growth of parasite in cultured infected erythrocytes is 2-3 times lower with fetal bovine serum in the culture liquide than with human serum | Plasmodium falciparum |
medicine | study on inhibitory effect of antimalarial drugs in clinical isolates of Plasmodium falciparum. No correlation between chloroquine or pyrimethamine and fosmidomycin. Fosmidomycin is moderately active against both chloroquine-susceptible and chloroquine-resistant isolates | Plasmodium falciparum |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Chloroquine | - |
Plasmodium falciparum | |
fosmidomycin | analysis of parasite growth in infected cultured erythrocytes. 50% growth inhibition at about 301 nM | Plasmodium falciparum | |
FR900098 | analysis of parasite growth in infected cultured erythrocytes. 50% growth inhibition at about 118 nM | Plasmodium falciparum | |
pyrimethamine | - |
Plasmodium falciparum |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Plasmodium falciparum | O96693 | clinical isolates | - |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.000301 | - |
- |
Plasmodium falciparum | fosmidomycin | |
0.118 | - |
- |
Plasmodium falciparum | FR900098 |