Activating Compound | Comment | Organism | Structure |
---|---|---|---|
Sodium phosphate | at pH 5.0-5.8 and pH 7.2 | Bos taurus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Cl- | at high ionic strength | Bos taurus | |
NaCl | - |
Bos taurus | |
NaNO3 | - |
Bos taurus | |
p-Carboxybenzaldehyde | substrate inhibition at higher concentration | Bos taurus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.285 | - |
Succinic semialdehyde | - |
Bos taurus | |
1.58 | - |
D-glucuronate | - |
Bos taurus | |
1.67 | - |
xylose | - |
Bos taurus | |
113 | - |
D-glucose 6-phosphate | - |
Bos taurus |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
31000 | - |
gel filtration | Bos taurus |
35100 | - |
1 * 35100, SDS-PAGE in presence of 2-mercaptoethanol | Bos taurus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
aldose + NAD(P)H | Bos taurus | - |
alditol + NAD(P)+ | - |
r |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Bos taurus | - |
ox, low-KM enzyme subtype | - |
Purification (Comment) | Organism |
---|---|
ox | Bos taurus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain | ox | Bos taurus | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
333.3 | - |
purified enzyme, with NADH in sodium phosphate buffer 100 mM, pH 7.0 | Bos taurus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
alditol + NAD(P)+ | - |
Bos taurus | aldose + NAD(P)H | - |
r | |
aldose + NAD(P)H | - |
Bos taurus | alditol + NAD(P)+ | - |
r | |
D-glucose 6-phosphate + NADPH + H+ | - |
Bos taurus | ? | - |
r | |
D-glucuronate + NAD(P)H | - |
Bos taurus | ? | - |
r | |
D-xylose + NAD(P)H | - |
Bos taurus | xylitol + NAD(P)+ | - |
r | |
pyridine-3-aldehyde + NAD(P)H | low-KM enzyme subtype | Bos taurus | 3-hydroxypyridine + NAD(P)+ | - |
r | |
succinic semialdehyde + NADH + H+ | - |
Bos taurus | 4-hydroxybutyrate + NAD+ | - |
? | |
xylitol + NAD(P)+ | - |
Bos taurus | D-xylose + NAD(P)H + H+ | - |
r |
Subunits | Comment | Organism |
---|---|---|
monomer | 1 * 35100, SDS-PAGE in presence of 2-mercaptoethanol | Bos taurus |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
6.2 | - |
- |
Bos taurus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADH | - |
Bos taurus | |
NADP+ | - |
Bos taurus |