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Literature summary for 1.1.1.188 extracted from
- Leishmania braziliensis prostaglandin F2alpha synthase impacts host infection (2020), Parasit. Vectors, 13, 009 .
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| cytoplasm | enriched in the secretory site of the parasite cell body, the flagellar pocket | Leishmania braziliensis | 5737 | - |
| flagellar pocket | - |
Leishmania braziliensis | - |
- |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Leishmania braziliensis | A0A3P3ZE14 | - |
- |
| Leishmania braziliensis MHOM/BR/75/M2904 | A0A3P3ZE14 | - |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| promastigote | promastigotes synthesize prostaglandin F2alpha in the presence of arachidonic acid, with peak production in the stationary growth phase under heat stress | Leishmania braziliensis | - |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| LBRM2904_31.2170 | - |
Leishmania braziliensis |
| PGF2S | - |
Leishmania braziliensis |
Expression
| Organism | Comment | Expression |
|---|---|---|
| Leishmania braziliensis | PGF2S is constitutively expressed throughout promastigote development | additional information |
General Information
| General Information | Comment | Organism |
|---|---|---|
| physiological function | overexpression of PGF2S leads to an increase of infectivity in vitro | Leishmania braziliensis |
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Release 2023.1 (January 2023)
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