Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
endoplasmic reticulum | - |
Homo sapiens | 5783 | - |
lipid droplet | surface of | Homo sapiens | 5811 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
4alpha-carboxy-4beta-methyl-5alpha-cholesta-8-en-3beta-ol + NADP+ | enzyme is involved in the sequential removal of two C-4 methyl groups in post-squalene cholesterol biosynthesis | Homo sapiens | 4alpha-methyl-5alpha-cholesta-8-en-3-one + NADPH + CO2 | - |
? | |
4alpha-carboxy-5alpha-cholesta-8-en-3beta-ol + NADP+ | enzyme is involved in the sequential removal of two C-4 methyl groups in post-squalene cholesterol biosynthesis | Homo sapiens | 5alpha-cholesta-8-en-3-one + CO2 + NADPH | - |
? |
Synonyms | Comment | Organism |
---|---|---|
C-3 sterol dehydrogenase(C-4 decarboxylase) | - |
Homo sapiens |
NSDHL | - |
Homo sapiens |
General Information | Comment | Organism |
---|---|---|
malfunction | mutations in NSDHL gene are associated with human CHILD syndrome, congenital hemidysplasia with ichthyosiform nevus and limb defects | Homo sapiens |