Activating Compound | Comment | Organism | Structure |
---|---|---|---|
Triton DF-18 | - |
Rattus sp. | |
Triton DF-18 | microsome-linked property to detergent-dependent release of activity for all mammalian, but not for rat enzyme | Mammalia |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
11beta,21-dihydroxypregn-4-en-3,20-dione + NADP+ | Mammalia | - |
21-hydroxy-pregn-4-en-3,11,20-trione + NADPH + H+ | - |
? | |
11beta,21-dihydroxypregn-4-en-3,20-dione + NADP+ | aves | - |
21-hydroxy-pregn-4-en-3,11,20-trione + NADPH + H+ | - |
? | |
11beta,21-dihydroxypregn-4-en-3,20-dione + NADP+ | dogfish | - |
21-hydroxy-pregn-4-en-3,11,20-trione + NADPH + H+ | - |
? | |
11beta,21-dihydroxypregn-4-en-3,20-dione + NADP+ | Rattus sp. | - |
21-hydroxy-pregn-4-en-3,11,20-trione + NADPH + H+ | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
aves | - |
- |
- |
dogfish | - |
- |
- |
Mammalia | - |
- |
- |
no activity in frog | - |
no activity for the oxidative direction in frog, toad, mud, puppy, shark and bird livers | - |
no activity in Necturus maculosus | - |
- |
- |
no activity in shark | - |
- |
- |
no activity in toad | - |
no activity for the oxidative direction in frog, toad, mud, puppy, shark and bird livers | - |
Rattus sp. | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Mammalia | - |
liver | - |
aves | - |
liver | - |
dogfish | - |
liver | - |
Rattus sp. | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
11beta,21-dihydroxypregn-4-en-3,20-dione + NADP+ | - |
Mammalia | 21-hydroxy-pregn-4-en-3,11,20-trione + NADPH + H+ | - |
? | |
11beta,21-dihydroxypregn-4-en-3,20-dione + NADP+ | - |
aves | 21-hydroxy-pregn-4-en-3,11,20-trione + NADPH + H+ | - |
? | |
11beta,21-dihydroxypregn-4-en-3,20-dione + NADP+ | - |
dogfish | 21-hydroxy-pregn-4-en-3,11,20-trione + NADPH + H+ | - |
? | |
11beta,21-dihydroxypregn-4-en-3,20-dione + NADP+ | - |
Rattus sp. | 21-hydroxy-pregn-4-en-3,11,20-trione + NADPH + H+ | - |
? |