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Information on EC 5.99.1.2 - DNA topoisomerase

for references in articles please use BRENDA:EC5.99.1.2

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transferred to EC 5.6.2.1
IUBMB Comments

These enzymes bring about the conversion of one topological isomer of DNA into another, e.g., the relaxation of superhelical turns in DNA, the interconversion of simple and knotted rings of single-stranded DNA, and the intertwisting of single-stranded rings of complementary sequences, cf. EC 5.6.1.2.2 DNA topoisomerase (ATP-hydrolysing).

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