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Information on EC 4.2.2.17 - inulin fructotransferase (DFA-I-forming)

for references in articles please use BRENDA:EC4.2.2.17

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IUBMB Comments

This enzyme, like EC 4.2.2.16 [levan fructotransferase (DFA-IV-forming)] and EC 4.2.2.18 [inulin fructotransferase (DFA-III-forming)], sequentially eliminates disaccharides from the non-reducing terminus of the fructan chain, with the disaccharide leaving as a difructose dianhydride. These enzymes have long been known as fructotransferases, so this is retained in the accepted name. Since the transfer is intramolecular, the reaction is an elimination and, hence, the enzyme is a lyase, belonging in EC 4.

The enzyme appears in viruses and cellular organisms

Synonyms
iftase, inulin fructotransferase (dfa i-producing), more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
Produces alpha-D-fructofuranose beta-D-fructofuranose 1,2':2,1'-dianhydride (DFA I) by successively eliminating the diminishing (2->1)-beta-D-fructan (inulin) chain from the terminal D-fructosyl-D-fructosyl disaccharide.
show the reaction diagram
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Highest Expressing Human Cell Lines
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