Any feedback?
Please rate this page
(enzyme.php)
(0/150)

BRENDA support

Disease on EC 3.1.11.4 - exodeoxyribonuclease (phage SP3-induced)

Please use the Disease Search for a specific query.
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
DISEASE
TITLE OF PUBLICATION
LINK TO PUBMED
Acquired Immunodeficiency Syndrome
A comparative study of preparation techniques for improving the viability of striatal grafts using vital stains, in vitro cultures, and in vivo grafts.
Caveolin-1-dependent infectious entry of human papillomavirus type 31 in human keratinocytes proceeds to the endosomal pathway for pH-dependent uncoating.
Recent advances in parapneumonic effusion and empyema.
Acute Coronary Syndrome
Coronary Neutrophil Extracellular Trap Burden and DNase Activity in ST-Elevation Acute Coronary Syndrome are Predictors of ST-Segment Resolution and Infarct Size.
Acute Kidney Injury
Rapid and sensitive detection of NGAL for the prediction of acute kidney injury via a polydopamine nanosphere/aptamer nanocomplex coupled with DNase I-assisted recycling amplification.
Adenocarcinoma
A successful liver metastasis model in mice with neuraminidase treated colon 26.
Actin-resistant DNAse I Expression From Oncolytic Adenovirus Enadenotucirev Enhances Its Intratumoral Spread and Reduces Tumor Growth.
Determination of DNA synthesis, estrogen receptors, and carcinoembryonic antigen in isolated cellular subpopulations of human breast cancer.
In silico functional pathway annotation of 86 established prostate cancer risk variants.
African Swine Fever
Single-stranded deoxyribonucleic acid nuclease induced by African swine fever virus and associated to the virion.
Airway Obstruction
DNase and atelectasis in non-cystic fibrosis pediatric patients.
Alcohol-Related Disorders
Incorporating Functional Genomic Information to Enhance Polygenic Signal and Identify Variants Involved in Gene-by-Environment Interaction for Young Adult Alcohol Problems.
Alzheimer Disease
Overexpression of DNAse I in brain of patients with Down syndrome.
Anaphylaxis
Anaphylaxis during autologous peripheral blood progenitor cell infusion.
Anemia
Dissection of the association status of two polymorphisms in the beta-globin gene cluster with variations in F-cell number in non-anemic individuals.
IFN regulatory factor (IRF) 3/7-dependent and -independent gene induction by mammalian DNA that escapes degradation.
Interferon-induced TRAIL-independent cell death in DNase II-/- embryos.
Regulation of the innate immune response by threonine-phosphatase of Eyes absent.
Requirement of DNase II for definitive erythropoiesis in the mouse fetal liver.
The story of DNase II: a stifled death-wish leads to self-harm.
Anemia, Hemolytic
Cell-Free DNA and DNase Activity in Dogs with Immune-Mediated Hemolytic Anemia.
Angioedema
Angioedema Associated With Nebulized Recombinant Human DNase in a Preterm Infant: Case Report.
Arthritis
Chronic polyarthritis caused by mammalian DNA that escapes from degradation in macrophages.
Cutting edge: AIM2 and endosomal TLRs differentially regulate arthritis and autoantibody production in DNase II-deficient mice.
Cytokine-dependent but acquired immunity-independent arthritis caused by DNA escaped from degradation.
IFN regulatory factor (IRF) 3/7-dependent and -independent gene induction by mammalian DNA that escapes degradation.
Local delivery of a recombinant adeno-associated vector containing a tumor necrosis factor-{alpha} antagonist gene in inflammatory arthritis: a phase 1 dose-escalation safety and tolerability study.
Monoclonal anti-HMGB1 antibody protection in two experimental arthritis models.
Protective targeting of high mobility group box chromosomal protein 1 in a spontaneous arthritis model.
Regulation of the innate immune response by threonine-phosphatase of Eyes absent.
STING manifests self DNA-dependent inflammatory disease.
Synergy between Hematopoietic and Radioresistant Stromal Cells Is Required for Autoimmune Manifestations of DNase II-/-IFNaR-/- Mice.
Arthritis, Juvenile
Cytokine-dependent but acquired immunity-independent arthritis caused by DNA escaped from degradation.
Arthritis, Psoriatic
Deoxyribonuclease activity of polyclonal IgGs: a putative serological marker in patients with spondyloarthritides.
Arthritis, Reactive
Deoxyribonuclease activity of polyclonal IgGs: a putative serological marker in patients with spondyloarthritides.
Arthritis, Rheumatoid
Chronic polyarthritis caused by mammalian DNA that escapes from degradation in macrophages.
Cytokine-dependent but acquired immunity-independent arthritis caused by DNA escaped from degradation.
FK506, an immunosuppressant, partially inhibits interleukin 6 production by adherent rheumatoid synovial cells.
Local delivery of a recombinant adeno-associated vector containing a tumor necrosis factor-{alpha} antagonist gene in inflammatory arthritis: a phase 1 dose-escalation safety and tolerability study.
T lymphocyte subclasses in rheumatoid synovia as analysed with monoclonal antibodies and functional in vitro tests.
Aspergillosis, Allergic Bronchopulmonary
Sequential bronchoscopy in the management of lobar atelectasis secondary to allergic bronchopulmonary aspergillosis.
Asthma
Endotracheal DNase for atelectasis in ventilated neonates.
Nebulised DNase in the treatment of life threatening asthma.
Nebulised DNase post-therapeutic bronchoalveolar lavage in near fatal asthma exacerbation in an adult patient refractory to conventional treatment.
Resolution of chronic atelectasis in a child with asthma after aerosolized recombinant human DNase.
The particularities of protein fraction in the apoptosis of lymphocytes of patients with asthma.
[Effectiveness of a DNAse aerosol in bronchial asthma]
Autoimmune Diseases
Analysis of deoxyribonuclease activity by conjugation-free fluorescence polarisation in sub-nanolitre droplets.
Cell-Free DNA and DNase Activity in Dogs with Immune-Mediated Hemolytic Anemia.
DNA-hydrolysing activity of IgG antibodies from the sera of patients with schizophrenia.
DNA-hydrolyzing activity of IgG antibodies from the sera of patients with diseases caused by different bacterial infections.
DNA-hydrolyzing activity of IgG antibodies from the sera of patients with tick-borne encephalitis.
Evaluation of all non-synonymous single nucleotide polymorphisms (SNPs) in the genes encoding human deoxyribonuclease I and I-like 3 as a functional SNP potentially implicated in autoimmunity.
Granule associated DNase in T4 and T8 lymphocytes from patients with autoimmune diseases.
Impaired deoxyribonuclease activity in monoglandular and polyglandular autoimmunity.
Interrogation of allelic chromatin states in human cells by high-density ChIP-genotyping.
Molecular basis of DNA recognition in the immune system.
Natural antibodies to nucleic acids.
SAMHD1 is a nucleic-acid binding protein that is mislocalized due to aicardi-goutières syndrome-associated mutations.
Six catalytic activities and cytotoxicity of immunoglobulin G and secretory immunoglobulin A from human milk.
The DNA-hydrolyzing activity of IgG antibodies from human placenta.
Bacteremia
Neutrophil extracellular traps (NETs) exacerbate severity of infant sepsis.
[Investigation on the etiology of sepsis by using experimental mouse model with leukocytopenia. 3. The role of Kupffer cells in the etiology of bacteremia]
Bacterial Infections
DNA-hydrolyzing activity of IgG antibodies from the sera of patients with diseases caused by different bacterial infections.
beta-Thalassemia
Dissection of the association status of two polymorphisms in the beta-globin gene cluster with variations in F-cell number in non-anemic individuals.
Blister
Export and intercellular transfer of DNA via membrane blebs of Neisseria gonorrhoeae.
Bluetongue
Identification of an antigenic peptide specific for bluetongue virus using phage display expression of NS1 sequences.
Brain Injuries
Traumatic injury is associated with reduced deoxyribonuclease activity and dysregulation of the actin scavenging system.
Breast Neoplasms
Association between TIMP-2 gene polymorphism and breast cancer in Han Chinese women.
Detection of estrogen receptors with monoclonal antibodies in routinely processed formalin-fixed paraffin sections of breast carcinoma. Use of DNase pretreatment to enhance sensitivity of the reaction.
Overexpression of lncRNA TATDN1 Promotes Cancer Cell Proliferation in Triple Negative Breast Cancer by Regulating miR-26b Methylation.
Prediction of response to neoadjuvant chemotherapy in breast cancer patients by circulating apoptotic biomarkers nucleosomes, DNAse, cytokeratin-18 fragments and survivin.
The association between telomerase activity and expression of its RNA component (hTR) in breast cancer patients: the importance of DNase treatment.
Bronchiectasis
Endotracheal DNase for atelectasis in ventilated neonates.
Mucolytics for bronchiectasis.
Short-term recombinant human DNase in bronchiectasis. Effect on clinical state and in vitro sputum transportability.
Treatment of idiopathic bronchiectasis with aerosolized recombinant human DNase I. rhDNase Study Group.
Bronchiolitis
DNase treatment for atelectasis in infants with severe respiratory syncytial virus bronchiolitis.
Endotracheal DNase for atelectasis in ventilated neonates.
Bronchitis
Antigenicity of the peplomer protein of infectious bronchitis virus.
Burkitt Lymphoma
DNase gamma-dependent and -independent apoptotic DNA fragmentations in Ramos Burkitt's lymphoma cell line.
Frequency and levels of antibodies to Epstein-Barr virus-specific DNase are elevated in patients with nasopharyngeal carcinoma.
Carcinogenesis
Agrobacterium tumefaciens deploys a superfamily of type VI secretion DNase effectors as weapons for interbacterial competition in planta.
Epstein-Barr virus DNase (BGLF5) induces genomic instability in human epithelial cells.
The regulation of albumin and alpha-fetoprotein gene expression in mammals.
[Histone specific proteinase and DNase activity of spleen lymphocyte nuclei during oncogenesis and under the effect of hydrobromide-5-(5',6' benzocoumaroyl-3')-methylaminouracil]
Carcinoma
A novel class of embryonic cell adhesion glycan epitopes is expressed in human colon carcinomas.
Alteration of the exDNA profile in blood serum of LLC-bearing mice under the decrease of tumour invasion potential by bovine pancreatic DNase I treatment.
Cladribine enhances apoptotic cell death in lung carcinoma cells over-expressing DNase ?.
Fine structural observation of a nucleolar-nuclear matrix-lamina-intermediate filament system in transformed cells.
Isolation and characterization of nuclear envelopes from three variant cell lines of the Shionogi mouse mammary carcinoma: identification of androgen-dependent peptides.
[Effect of tumor growth and preliminary irradiation on the state of DNA degradation processes in the liver cell nuclei]
[Extracellular DNA fragments and DNAse activity in blood serum of rats with transplantated Guerin's carcinoma after multiple exposures to low doses of X-irradiation]
[Molecular mechanisms of biological action of low magnetic fields. I. Stability of chromatin from Ehrlich ascite carcinoma and mouse brain cells to the treatment of DNase 1 under combined action of low constant and alternating low-frequency magnetic fields adjusted to the cyclotron resonance of ions of polar amino acids]
[Ol'ha Petrivna Chepinoha--a founder of investigations of nucleic acids in biochemistry in Ukraine. To the 100th anniversary of birthday, 1.07.1907--27.04.1983]
Carcinoma, Embryonal
Expression of c-myb in embryonal carcinoma cells and embryonal stem cells.
Three-dimensional distribution of DNase I-sensitive chromatin regions in interphase nuclei of embryonal carcinoma cells.
Carcinoma, Hepatocellular
Alteration of the exDNA profile in blood serum of LLC-bearing mice under the decrease of tumour invasion potential by bovine pancreatic DNase I treatment.
Alternative inducers of the rat metallothionein I gene cause distinct changes in chromatin structure in the 5' region of the gene.
Nuclear topoisomerase I and DNase activities in rat diethylnitrosamine-induced hepatoma, in regenerating and fetal liver.
Partial activation of gene activity and chromatin remodeling of the human 14q32.1 serpin gene cluster by HNF-1 alpha and HNF-4 in fibroblast microcell hybrids.
Regulation of the alpha-fetoprotein promoter: Ku binding and DNA spatial conformation.
Specific sets of DNase I-hypersensitive sites are associated with the potential and overt expression of the rat albumin and alpha-fetoprotein genes.
Systematical analyses of variants in DNase I hypersensitive sites to identify hepatocellular carcinoma susceptibility loci in a Chinese population.
The human growth hormone receptor gene - characterisation of the liver-specific promoter.
[Enzymes of anabolic and catabolic nucleic acid pathways in human hepatomas, in liver of healthy persons, and in liver of patients with cancer of gastrointestinal tract]
Carcinoma, Lewis Lung
Alteration of the exDNA profile in blood serum of LLC-bearing mice under the decrease of tumour invasion potential by bovine pancreatic DNase I treatment.
Carcinoma, Squamous Cell
Characterization and sequence of the promoter region of the human epidermal growth factor receptor gene.
Cardiomyopathies
Mitochondrial DNA that escapes from autophagy causes inflammation and heart failure.
Cataract
DNase activity in murine lenses: implications for cataractogenesis.
HSF4 regulates DLAD expression and promotes lens de-nucleation.
Involvement of DNase II-like acid DNase in the cataract formation of the UPL rat and the Shumiya cataract rat.
Cholangitis, Sclerosing
Segregation of pANCA antigenic recognition by DNase treatment of neutrophils: ulcerative colitis, type 1 autoimmune hepatitis, and primary sclerosing cholangitis.
Cholera
Biochemical characterization of extracellular proteases from Vibrio cholerae.
Chromoblastomycosis
Secretion of five extracellular enzymes by strains of chromoblastomycosis agents.
Colitis
Neutrophil Extracellular Traps Induce Intestinal Damage and Thrombotic Tendency in Inflammatory Bowel Disease.
Colitis, Ulcerative
Segregation of pANCA antigenic recognition by DNase treatment of neutrophils: ulcerative colitis, type 1 autoimmune hepatitis, and primary sclerosing cholangitis.
Colorectal Neoplasms
Immunogenic cell death biomarkers HMGB1, RAGE, and DNAse indicate response to radioembolization therapy and prognosis in colorectal cancer patients.
Metastatic potential of human colorectal carcinomas implanted into nude mice: prediction of clinical outcome in patients operated upon for cure.
Telomerase expression of malignant epithelial cells correlates with Dukes' stage in colorectal cancer.
Tumor-derived suppressor factors (TDSFs) in normal and neoplastic colon and rectum.
Coma
ComA, a phosphorylated response regulator protein of Bacillus subtilis, binds to the promoter region of srfA.
Communicable Diseases, Emerging
Ehrlichia chaffeensis Uses an Invasin To Suppress Reactive Oxygen Species Generation by Macrophages via CD147-Dependent Inhibition of Vav1 To Block Rac1 Activation.
Connective Tissue Diseases
Effect of enzyme treatment of Chrithidia luciliae on the reactivity of its kinetoplast with anti-DNA sera.
Cough
Noninvasive clearance of airway secretions.
COVID-19
Defective NET clearance contributes to sustained FXII activation in COVID-19-associated pulmonary thrombo-inflammation.
Elastase and exacerbation of neutrophil innate immunity are involved in multi-visceral manifestations of COVID-19.
Proteome Profiling of Recombinant DNase Therapy in Reducing NETs and Aiding Recovery in COVID-19 Patients.
The Balance of Neutrophil Extracellular Trap Formation and Nuclease Degradation: an Unknown Role of Bacterial Coinfections in COVID-19 Patients?
Cowpox
In situ assay of poxvirus-induced and virion-contained deoxyribonucleases in DNA polyacrylamide gels.
Cross Infection
[Pseudomonas aeruginosa and cystic fibrosis: non-antibiotic strategy]
Cystic Fibrosis
Aerosolized recombinant human DNase in hospitalized cystic fibrosis patients with acute pulmonary exacerbations.
An update on bronchiectasis.
Anionic poly(amino acid)s dissolve F-actin and DNA bundles, enhance DNase activity, and reduce the viscosity of cystic fibrosis sputum.
Bronchoscopically administered recombinant human DNase for lobar atelectasis in cystic fibrosis.
Clinical benefit from nebulized human recombinant DNase in Kartagener's syndrome.
Clinical trials of recombinant human DNase in cystic fibrosis patients.
Cloning and characterization of a novel human DNase.
Comparison of the in vitro and in vivo response to inhaled DNase in patients with cystic fibrosis.
Cost of care for individuals with cystic fibrosis: a regression approach to determining the impact of recombinant human DNase.
Cough suppressant and pharmacologic protussive therapy: ACCP evidence-based clinical practice guidelines.
Deoxyribonucleases and Their Applications in Biomedicine.
Development of an analytical HPLC methodology to study the effects of thymosin ?4 on actin in sputum of cystic fibrosis patients.
DNA concentration and length in sputum of patients with cystic fibrosis during inhalation with recombinant human DNase.
DNA concentrations in BAL fluid of cystic fibrosis patients with early lung disease: influence of treatment with dornase alpha.
DNase in cystic fibrosis: the challenge of assessing response and maximising benefit.
DNase in stable cystic fibrosis infants: a pilot study.
DNase trials in cystic fibrosis.
DNase use in the daily care of cystic fibrosis: who benefits from it and to what extent? Results of a cohort study of 199 patients in 13 centres. DNase National Study Group.
Dose-dependent in vitro effect of recombinant human DNase on rheological and transport properties of cystic fibrosis respiratory mucus.
Effect of aerosolized recombinant human DNase on exacerbations of respiratory symptoms and on pulmonary function in patients with cystic fibrosis. The Pulmozyme Study Group.
Effect of DNase on exercise capacity in cystic fibrosis.
Effect of DNase on the activity of neutrophil elastase, cathepsin G and proteinase 3 in the presence of DNA.
Effect of nebulised recombinant DNase on neutrophil elastase load in cystic fibrosis.
Effect of smaller droplet size of dornase alfa on lung function in mild cystic fibrosis. Dornase Alfa Nebulizer Group.
Effects of 12-week administration of dornase alfa in patients with advanced cystic fibrosis lung disease. Pulmozyme Study Group.
Effects of recombinant human DNase and hypertonic saline on airway inflammation in children with cystic fibrosis.
Effects of recombinant human DNase therapy on healthcare use and costs in patients with cystic fibrosis.
Effects of repetitive use and cleaning techniques of disposable jet nebulizers on aerosol generation.
Efficacy of human recombinant DNase in pediatric patients with cystic fibrosis.
Endotracheal DNase for atelectasis in ventilated neonates.
Enhancement of Pulmozyme activity in purulent sputum by combination with poly-aspartic acid or gelsolin.
Health-related quality of life for adults with cystic fibrosis: a regression approach to assessing the impact of recombinant human DNase.
High-dose pancreatic-enzyme supplements and fibrosing colonopathy in children with cystic fibrosis.
Human recombinant DNase in cystic fibrosis.
Importance of DNase and alginate lyase for enhancing free and liposome encapsulated aminoglycoside activity against Pseudomonas aeruginosa.
Improvement of cystic fibrosis airway mucus transportability by recombinant human DNase is related to changes in phospholipid profile.
Multicenter, open-label study of recombinant human DNase in cystic fibrosis patients with moderate lung disease. DNase International Study Group.
Neutrophil elastase enhances sputum solubilization in cystic fibrosis patients receiving DNase therapy.
Oxidative stress regulates CFTR gene expression in human airway epithelial cells through a distal antioxidant response element.
Pharmacoeconomic review of recombinant human DNase in the management of cystic fibrosis.
Pharmacology, clinical efficacy and safety of recombinant human DNase in cystic fibrosis.
Plasmid DNA molecules complexed with cationic liposomes are protected from degradation by nucleases and shearing by aerosolisation.
Pseudomonas aeruginosa produces an extracellular deoxyribonuclease that is required for utilization of DNA as a nutrient source.
Recombinant DNase in cystic fibrosis: a protocol for targeted introduction through n-of-1 trials. Scottish Cystic Fibrosis Group.
Recombinant human DNase (rhDNase) in cystic fibrosis: is it cost effective?
Recombinant human DNase (rhDNase) influences phospholipid composition, surface activity, rheology and consecutively clearance indices of cystic fibrosis sputum.
Recombinant human DNase in cystic fibrosis.
Recombinant human DNase inhalation in normal subjects and patients with cystic fibrosis. A phase 1 study.
Recombinant human DNase nebulisation in children with cystic fibrosis: before bedtime or after waking up?
Sequential bronchoscopy in the management of lobar atelectasis secondary to allergic bronchopulmonary aspergillosis.
Short-term efficacy of ultrasonically nebulized hypertonic saline in cystic fibrosis.
Short-term recombinant human DNase in bronchiectasis. Effect on clinical state and in vitro sputum transportability.
Targeting DNase in cystic fibrosis.
The effects of recombinant human DNase on neutrophil elastase activity and interleukin-8 levels in the sputum of patients with cystic fibrosis.
The genetics of cystic fibrosis: a paradigm for uncovering new drug targets.
The role of dornase alfa in the treatment of cystic fibrosis.
The role of recombinant human DNase in the treatment of patients with cystic fibrosis: many promises, more problems.
Update on long-term outcomes for chronic rhinosinusitis in cystic fibrosis.
Use of computerized tomography and chest x-rays in evaluating efficacy of aerosolized recombinant human DNase in cystic fibrosis patients younger than age 5 years: a preliminary study.
Using Pulmozyme DNase treatment in lentiviral vector production.
[Cystic fibrosis. Current indications for nebulized treatments: antibiotics and DNase]
[Cystic fibrosis: current therapy. Inhalation therapy with recombinant DNAse]
[Determination of DNase activity in the sweat and the urine. Micro disc-electrophoretic assay in health and mucoviscidosis disease (author's transl)]
[Recombinant human DNase in conditions other than cystic fibrosis]
[Socioeconomic evaluation of the effect of rhDNase on the cost of treating infections of the respiratory tract in patients with cystic fibrosis]
Cysts
Carbohydrate analysis of Acanthamoeba castellanii.
Decompression Sickness
Intrinsic bends and integration host factor binding at F plasmid oriT.
Diabetes Mellitus
Clinical investigation of serum deoxyribonuclease: II. Clinical studies of serum deoxyribonuclease activity in pancreatic disease.
Diabetes Mellitus, Type 1
Impaired deoxyribonuclease activity in monoglandular and polyglandular autoimmunity.
Diabetic Cardiomyopathies
Streptozotocin-induced diabetic cardiomyopathy in rats: ameliorative effect of PIPERINE via Bcl2, Bax/Bcl2, and caspase-3 pathways.
Diphtheria
Strain-dependent arthritogenic potential of the zoonotic pathogen Corynebacterium ulcerans.
Dry Eye Syndromes
A Phase I/II Placebo-Controlled Randomized Pilot Clinical Trial of Recombinant Deoxyribonuclease (DNase) Eye Drops Use in Patients With Dry Eye Disease.
Ehrlichiosis
Ehrlichia chaffeensis Uses an Invasin To Suppress Reactive Oxygen Species Generation by Macrophages via CD147-Dependent Inhibition of Vav1 To Block Rac1 Activation.
Empyema
Alteplase and DNase for the treatment of pleural empyema in rats.
Effects of streptokinase and deoxyribonuclease on viscosity of human surgical and empyema pus.
Intrapleural heparin or heparin combined with human recombinant DNase is not effective in the treatment of empyema in a rabbit model.
Intrapleural therapy.
Intrapleural tissue plasminogen activator and deoxyribonuclease therapy for pleural infection.
Management of Pleural Infection.
Recent advances in parapneumonic effusion and empyema.
Successful treatment of empyema thoracis with human recombinant deoxyribonuclease.
Tissue plasminogen activator and DNase in empyema.
Empyema, Pleural
Alteplase and DNase for the treatment of pleural empyema in rats.
Effectiveness of Intrapleural Tissue Plasminogen Activator and Dornase Alfa vs Tissue Plasminogen Activator Alone in Children with Pleural Empyema: A Randomized Clinical Trial.
Intrapleural administration of DNase alone for pleural empyema.
Encephalitis, Tick-Borne
DNA-hydrolyzing activity of IgG antibodies from the sera of patients with tick-borne encephalitis.
Encephalomyelitis
Discovery of a novel human picornavirus in a stool sample from a pediatric patient presenting with fever of unknown origin.
Epstein-Barr Virus Infections
Prevalence of antibody to Epstein-Barr virus DNase in children.
exodeoxyribonuclease (phage sp3-induced) deficiency
Morphological alterations and DNase deficiency in phenobarbital promotion of N-nitrosomorpholine initiated rat hepatocarcinogenesis.
Reversibility of acid and alkaline deoxyribonuclease deficiency in malignant tumor cells.
Fasciitis, Necrotizing
DNase Expression Allows the Pathogen Group A Streptococcus to Escape Killing in Neutrophil Extracellular Traps.
Mitogenic factor (MF) is the major DNase of serotype M89 Streptococcus pyogenes.
Fatigue Syndrome, Chronic
Antibodies to Epstein-Barr virus-specific DNase and DNA polymerase in the chronic fatigue syndrome.
Fibroma
Highly sensitive nuclease assays based on chemically modified DNA or RNA.
Fibrosarcoma
Soluble factors from murine and human tumors induce suppressor cells.
Ganglion Cysts
[Experimental study of primary culture methods for spiral ganglion cells of newborn rats]
Genetic Diseases, Inborn
[Dynamic of DNAse activity induction in serum of normal animals after heterogeneous DNA injection and in hereditary pathology]
Glioma
Astrocyte-specific expression of the alpha1-antichymotrypsin and glial fibrillary acidic protein genes requires activator protein-1.
Nuclear factor-1-X regulates astrocyte-specific expression of the alpha1-antichymotrypsin and glial fibrillary acidic protein genes.
Glomerulonephritis
Neutrophil Extracellular Traps (NETs) profiles in patients with incident SLE and lupus nephritis.
glucan 1,4-alpha-glucosidase deficiency
Deletion polymorphism of DNASE1L1, an X-linked DNase I-like gene, in acid maltase deficiency disorders.
Glycogen Storage Disease Type II
Deletion polymorphism of DNASE1L1, an X-linked DNase I-like gene, in acid maltase deficiency disorders.
Goiter
Comparison of the Level of DNA-Hydrolyzing Polyclonal IgG Antibodies in Sera of Patients with Hashimoto's Thyroiditis and Nontoxic Nodal Goiter.
Effect of different drugs on the level of DNA-hydrolyzing polyclonal IgG antibodies in sera of patients with Hashimoto's thyroiditis and nontoxic nodal goiter.
Granulomatous Disease, Chronic
Effect of human polymorphonuclear and mononuclear leukocytes on chromosomal and plasmid DNA of Escherichia coli. Role of acid DNase.
Heart Arrest
Imbalance between plasma double-stranded DNA and deoxyribonuclease activity predicts mortality after out-of-hospital cardiac arrest.
Heart Failure
Long Term Effects of AAV1/SERCA2a Gene Transfer in Patients with Severe Heart Failure: Analysis of Recurrent Cardiovascular Events and Mortality.
Hepatitis
Repeated exposure to trace amounts of woodchuck hepadnavirus induces molecularly evident infection and virus-specific T cell response in the absence of serological infection markers and hepatitis.
The spectrum of complement-fixing antinuclear antibodies in patients with hepatocellular carcinoma.
Hepatitis B
Differential activation of hepatitis B DNA polymerase by detergent and salt.
Production and Function of the Cytoplasmic Deproteinized Relaxed Circular DNA of Hepadnaviruses.
Vaccine against human hepatitis B virus prepared from antigen derived from human hepatoma cells in culture.
Hepatitis C
In situ amplification using universal energy transfer-labeled primers.
Localization of hepatitis C virus RNA in human liver biopsies by in situ hybridization using thymine-thymine dimerized oligo DNA probes: improved method.
Hepatitis, Autoimmune
Segregation of pANCA antigenic recognition by DNase treatment of neutrophils: ulcerative colitis, type 1 autoimmune hepatitis, and primary sclerosing cholangitis.
Herpes Simplex
Comparison of exonucleolytic activities of herpes simplex virus type-1 DNA polymerase and DNase.
DNase induced after infection of KB cells by herpes simplex virus type 1 or type 2. II. Characterization of an associated endonuclease activity.
Expression analysis of recombinant herpes simplex virus type 1 DNase.
Frequency and levels of antibodies to Epstein-Barr virus-specific DNase are elevated in patients with nasopharyngeal carcinoma.
Herpes simplex virus type 1 DNase: functional analysis of the enzyme expressed by recombinant baculovirus.
Mechanism of degradation of duplex DNA by the DNase induced by herpes simplex virus.
Mutant of herpes simplex virus type 2 with temperature-sensitive lesions affecting virion thermostability and DNase activity: identification of the lethal mutation and physical mapping of the nuc-lesion.
Nucleocapsid, nuclear association, and genome location of the herpes simplex virus type 2 38-kD DNA-binding protein.
Ultraviolet irradiation of herpes simplex virus (type 1): delayed transcription and comparative sensitivites of virus functions.
Histiocytic Necrotizing Lymphadenitis
Involvement of DNase gamma in apoptotic DNA fragmentation in histiocytic necrotizing lymphadenitis.
Huntington Disease
Age at onset of Huntington disease is not modulated by the R72P variation in TP53 and the R196K variation in the gene coding for the human caspase activated DNase (hCAD).
Modulation of age at onset of Huntington disease patients by variations in TP53 and human caspase activated DNase (hCAD) genes.
Hypersensitivity
A conserved sequence in the immunoglobulin J kappa-C kappa intron: possible enhancer element.
A detailed protocol for formaldehyde-assisted isolation of regulatory elements (FAIRE).
A Functional Variant Associated with Atrial Fibrillation Regulates PITX2c Expression through TFAP2a.
A likelihood approach to testing hypotheses on the co-evolution of epigenome and genome.
A region in the CD8 gene locus that directs expression to the mature CD8 T cell subset in transgenic mice.
A tiling-deletion-based genetic screen for cis-regulatory element identification in mammalian cells.
An inducible enhancer required for Il12b promoter activity in an insulated chromatin environment.
Analysis of chromosomes with restriction endonucleases and DNase hypersensitivity.
Aniridia-associated translocations, DNase hypersensitivity, sequence comparison and transgenic analysis redefine the functional domain of PAX6.
Association and spreading of the Drosophila dosage compensation complex from a discrete roX1 chromatin entry site.
Associations between potentially functional CORIN SNPs and serum corin levels in the Chinese Han population.
Atlas of Transcription Factor Binding Sites from ENCODE DNase Hypersensitivity Data across 27 Tissue Types.
Bright/ARID3A contributes to chromatin accessibility of the immunoglobulin heavy chain enhancer.
Browsing (Epi)genomes: a guide to data resources and epigenome browsers for stem cell researchers.
CHD6 regulates the topological arrangement of the CFTR locus.
CHIPIN: ChIP-seq inter-sample normalization based on signal invariance across transcriptionally constant genes.
Combinatorial regulation of a Blimp1 (Prdm1) enhancer in the mouse retina.
Coupling transcription factor occupancy to nucleosome architecture with DNase-FLASH.
Deep learning for genomics using Janggu.
Definition, conservation and epigenetics of housekeeping and tissue-enriched genes.
Detection of active transcription factor binding sites with the combination of DNase hypersensitivity and histone modifications.
Differentially methylated CpG island within human XIST mediates alternative P2 transcription and YY1 binding.
Distant conserved sequences flanking endothelial-specific promoters contain tissue-specific DNase-hypersensitive sites and over-represented motifs.
Distinct epigenetic features of differentiation-regulated replication origins.
DNA clustering and genome complexity.
DNA Methylation and DNase-Hypersensitive Sites in the 5' Flanking and Transcribed Regions of the Rat Preproenkephalin Gene: Studies of Mediobasal Hypothalamus.
DNA sequence changes in an upstream DNase I-hypersensitive region are correlated with reduced gene expression.
DNase hypersensitivity and methylation of the human CD3G and D genes during T-cell development.
DNase I Digestion of Isolated Nulcei for Genome-Wide Mapping of DNase Hypersensitivity Sites in Chromatin.
Dynamic, sex-differential STAT5 and BCL6 binding to sex-biased, growth hormone-regulated genes in adult mouse liver.
Dysregulation of Synaptic Signaling Genes Is Involved in Biology of Uterine Leiomyoma.
Efficient genome editing in hematopoietic stem cells with helper-dependent Ad5/35 vectors expressing site-specific endonucleases under microRNA regulation.
Enhancer networks revealed by correlated DNAse hypersensitivity states of enhancers.
Epigenomic functional characterization of genetic susceptibility variants in systemic vasculitis.
Extremely rare variants reveal patterns of germline mutation rate heterogeneity in humans.
Fine-scale mapping of the FGFR2 breast cancer risk locus: putative functional variants differentially bind FOXA1 and E2F1.
Functional dissection of the murine lck distal promoter.
Functional validation of a constitutive autonomous silencer element.
Fusarium solani DNase is a signal for increasing expression of nonhost disease resistance response genes, hypersensitivity, and pisatin production.
GAGA factor-dependent transcription and establishment of DNase hypersensitivity are independent and unrelated events in vivo.
Genetic insights into juvenile idiopathic arthritis derived from deep whole genome sequencing.
Genome-wide DNase hypersensitivity, and occupancy of RUNX2 and CTCF reveal a highly dynamic gene regulome during MC3T3 pre-osteoblast differentiation.
Genome-wide meta-analysis reveals shared new loci in systemic seropositive rheumatic diseases.
Gestational Vitamin D Supplementation Leads to Reduced Perinatal RXRA DNA Methylation: Results From the MAVIDOS Trial.
Human CD8 alpha expression in NK cells but not cytotoxic T cells of transgenic mice.
Identification and Characterization of Enhancer-Blocking Insulators to Reduce Retroviral Vector Genotoxicity.
Impact of CAR agonist ligand TCPOBOP on mouse liver chromatin accessibility.
Impact of CUX2 on the Female Mouse Liver Transcriptome: Activation of Female-biased Genes and Repression of Male-biased Genes.
In silico functional pathway annotation of 86 established prostate cancer risk variants.
Interferon regulatory factors are transcriptional regulators of adipogenesis.
Isolation of Nuclei for Use in Genome-Wide DNase Hypersensitivity Assays to Probe Chromatin Structure.
Late-replicating heterochromatin is characterized by decreased cytosine methylation in the human genome.
Localization of DNase I-hypersensitive regions during rat spermatogenesis: stage-dependent patterns and unique sensitivity of elongating spermatids.
Localized DNA cleavage secondary to genotoxic exposure adjacent to an Alu inverted repeat.
Long non-coding RNAs discriminate the stages and gene regulatory states of human humoral immune response.
Longitudinal analysis of epigenome-wide DNA methylation reveals novel smoking-related loci in African Americans.
Motif analysis in DNAse hypersensitivity regions uncovers distal cis elements associated with gene expression.
Multiplex indexing approach for the detection of DNase I hypersensitive sites in single cells.
Mutational analysis of the trans-activation-responsive region of the human immunodeficiency virus type I long terminal repeat.
MYC oncogene involved in a t(8;22) chromosome translocation is not altered in its putative regulatory regions.
Native genomic blotting: high-resolution mapping of DNase I-hypersensitive sites and protein-DNA interactions.
NF-kappa B regulates BCL3 transcription in T lymphocytes through an intronic enhancer.
Nuclear protein binding to octamer motifs in the immunoglobulin gamma 1 switch region.
Nucleic acid sequence and DNase hypersensitive sites of the 5' region of the mouse progesterone receptor gene.
Pathways- and epigenetic-based assessment of relative immune infiltration in various types of solid tumors.
Patterns of DNase sensitivity in the chromosomes of Rana perezi (Amphibia: Anura).
Poly(ADP-ribose)-dependent chromatin unfolding facilitates the association of DNA-binding proteins with DNA at sites of damage.
Prediction Of Histone Post-Translational Modifications Using Deep Learning.
PTSD and the klotho longevity gene: Evaluation of longitudinal effects on inflammation via DNA methylation.
RBPJ binds to consensus and methylated cis elements within phased nucleosomes and controls gene expression in human aortic smooth muscle cells in cooperation with SRF.
Reconstructing A/B compartments as revealed by Hi-C using long-range correlations in epigenetic data.
Regulatory variants of FOXG1 in the context of its topological domain organisation.
Remarkable site specificity of local transposition into the Hsp70 promoter of Drosophila melanogaster.
RNA:DNA hybrids in the human genome have distinctive nucleotide characteristics, chromatin composition, and transcriptional relationships.
Role of chromatin structure in integration of helper-dependent adenoviral vectors containing the beta-globin locus control region.
SNP in human ARHGEF3 promoter is associated with DNase hypersensitivity, transcript level and platelet function, and Arhgef3 KO mice have increased mean platelet volume.
Statistics for ChIP-chip and DNase hypersensitivity experiments on NimbleGen arrays.
Structural analysis of ternary complexes of vaccinia RNA polymerase.
Structural characterization and tissue-specific expression of the mouse glucose-6-phosphate dehydrogenase gene.
Structure-function analysis of the herpes simplex virus type 1 UL12 gene: correlation of deoxyribonuclease activity in vitro with replication function.
SV40-alpha-globulin hybrid minichromosomes. Differences in DNase I hypersensitivity of promoter and enhancer sequences.
Systemic Investigation of Promoter-wide Methylome and Genome Variations in Gout.
The 3'-J? Region of the TCR? Locus Bears Gene Regulatory Activity in Thymic and Peripheral T Cells.
The Circadian Rhythm Gene Arntl2 Is a Metastasis Susceptibility Gene for Estrogen Receptor-Negative Breast Cancer.
The distribution of genes on human chromosomes as studied by in situ nick translation.
The stress protein ERp57/GRP58 binds specific DNA sequences in HeLa cells.
Thyroid hormone, glucagon, and medium-chain fatty acids regulate transcription initiated from promoter 1 and promoter 2 of the acetyl-CoA carboxylase-alpha gene in chick embryo hepatocytes.
Transcription factor-dependent chromatin remodeling of Il18r1 during Th1 and Th2 differentiation.
Transcription of the S gene in transgenic mice is associated with hypomethylation at specific sites and with DNase I sensitivity.
Transcription-coupled genetic instability marks acute lymphoblastic leukemia structural variation hotspots.
Transcriptionally active regions are the preferred targets for chromosomal HPV integration in cervical carcinogenesis.
Unbiased, Genome-wide in vivo Mapping of Transcriptional Regulatory Elements Reveals Sex Differences in Chromatin Structure Associated with Sex-specific Liver Gene Expression.
Understanding transcriptional regulation by integrative analysis of transcription factor binding data.
Using genomic annotations increases statistical power to detect eGenes.
Visualizing complex feature interactions and feature sharing in genomic deep neural networks.
Hypertension
Detection of Putative Functional Single Nucleotide Polymorphisms in Blood Pressure Loci and Validation of Association Between Single Nucleotide Polymorphism in WBP1L and Hypertension in the Chinese Han Population.
SNPs rs10224002 in PRKAG2 may disturb gene expression and consequently affect hypertension.
Infections
A deoxyribonuclease found after infection of Bacillus subtilis with phage SP3.
A naturally occurring mutation in ropB suppresses SpeB expression and reduces M1T1 group A streptococcal systemic virulence.
A review of the management of complex para-pneumonic effusion in adults.
ACP Journal Club. Intrapleural t-PA plus DNase improved clinical outcomes in patients with pleural infection.
Adenovirus DNA is associated with the nuclear matrix of infected cells.
Adenovirus-induced inhibition of cellular DNase.
Antibodies to Epstein-Barr virus-specific DNase and DNA polymerase in the chronic fatigue syndrome.
Assembly of human papillomavirus type 16 pseudovirions in Saccharomyces cerevisiae.
Biological effect of tissue plasminogen activator (t-PA) and DNase intrapleural delivery in pleural infection patients.
Blow fly Lucilia sericata nuclease digests DNA associated with wound slough/eschar and with Pseudomonas aeruginosa biofilm.
Changes in DNase activities in Bacillus subtilis infected with bacteriophage PBS 1.
Chromatin structure of simian virus 40-pBR322 recombinant plasmids in COS-1 cells.
Concurrent Intrapleural Instillation of Tissue Plasminogen Activator and DNase for Pleural Infection. A Single-Center Experience.
Cost-effectiveness of intrapleural use of tissue plasminogen activator and DNase in pleural infection: evidence from the MIST2 randomised controlled trial.
Demonstration of the human herpesvirus 6-induced DNA polymerase and DNase.
Detection of infectious adenovirus in cell culture by mRNA reverse transcription-PCR.
DNA-fragmentation is a source of bactericidal activity against Pseudomonas aeruginosa.
DNase Expression Allows the Pathogen Group A Streptococcus to Escape Killing in Neutrophil Extracellular Traps.
DNase II deficiency impairs innate immune function in Drosophila.
DNase induced after infection of KB cells by herpes simplex virus type 1 or type 2. II. Characterization of an associated endonuclease activity.
Dose De-Escalation of Intrapleural Tissue Plasminogen Activator Therapy for Pleural Infection: The ADAPT Project.
Effect of aerosolized rhDNase (Pulmozyme(R)) on pulmonary colonization in patients with cystic fibrosis.
Effects of recombinant human DNase therapy on healthcare use and costs in patients with cystic fibrosis.
Ehrlichia chaffeensis Uses Its Surface Protein EtpE to Bind GPI-Anchored Protein DNase X and Trigger Entry into Mammalian Cells.
Empyema thoracis.
Enhanced nasopharyngeal infection and shedding associated with an epidemic lineage of emm3 group A Streptococcus.
Enhancement of Shiga toxin production in enterohemorrhagic Escherichia coli serotype O157:H7 by DNase colicins.
Escherichia coli Uropathogenic-Specific Protein, Usp, Is a Bacteriocin-Like Genotoxin.
Evaluation of methods for hepatitis C virus detection in archival liver biopsies. Comparison of histology, immunohistochemistry, in-situ hybridization, reverse transcriptase polymerase chain reaction (RT-PCR) and in-situ RT-PCR.
Evidence for an "early early" vaccinia virus-induced protein which causes a density change of infected L-M cells.
Expression analysis of recombinant herpes simplex virus type 1 DNase.
Expression and characterization of a DNase I-Fc fusion enzyme.
Extracellular deoxyribonuclease made by group A Streptococcus assists pathogenesis by enhancing evasion of the innate immune response.
Extracellular DNA, cell surface proteins and c-di-GMP promote biofilm formation in Clostridioides difficile.
Formation in the dark, of virus-induced deoxyribonuclease activity in Anacystis nidulans, an obligate photoautotroph.
Functional analysis of Streptococcus pyogenes nuclease A (SpnA), a novel group A streptococcal virulence factor.
Group A Streptococcal DNase Sda1 Impairs Plasmacytoid Dendritic Cells' Type 1 Interferon Response.
Identification of an insulator in AAVS1, a preferred region for integration of adeno-associated virus DNA.
In vitro transactivation of baculovirus early genes by nuclear extracts from Autographa californica nuclear polyhedrosis virus-infected Spodoptera frugiperda cells.
In vitro transcription by cytoplasmic extracts from cells infected with African swine fever virus.
Intrapleural Fibrinolytics and Deoxyribonuclease for Treatment of Indwelling Pleural Catheter-Related Pleural Infection: A Multi-Center Observational Study.
Intrapleural therapy in management of complicated parapneumonic effusions and empyema.
Intrapleural use of tissue plasminogen activator and DNase in pleural infection.
Intrapleural use of urokinase and DNase in pleural infections managed with repeated thoracentesis: A comparative cohort study.
Mucolytics for bronchiectasis.
Neutrophil Extracellular Traps Effectively Control Acute Chikungunya Virus Infection.
Neutrophil extracellular traps in the host defense against sepsis induced by Burkholderia pseudomallei (melioidosis).
New strategies to manage complicated pleural effusions.
Phage adsorption and productive lysis in stable protoplast type L-forms of Bacillus subtilis and Streptomyces hygroscopicus.
Physical and functional properties of airway secretions in cystic fibrosis--therapeutic approaches.
Potyviral NIa proteinase, a proteinase with novel deoxyribonuclease activity.
Production of coagulase, deoxyribonuclease and heat-stable deoxyribonuclease by canine isolates of staphylococci.
Production of extracellular enzymes by Microsporum canis and their role in its virulence.
Quorum Sensing as a Target for Controlling Surface Associated Motility and Biofilm Formation in Acinetobacter baumannii ATCC® 17978TM.
Recent developments in the management of pleural infection: A comprehensive review.
Recombinant human DNase in children with airway malacia and lower respiratory tract infection.
Recombinant pseudorabies virus DNase exhibits a RecBCD-like catalytic function.
Role of Bacterial and Host DNases on Host-Pathogen Interaction during Streptococcus suis Meningitis.
Safety and Efficacy of Intrapleural Tissue Plasminogen Activator and DNase during Extended Use in Complicated Pleural Space Infections.
Single-stranded deoxyribonucleic acid nuclease induced by African swine fever virus and associated to the virion.
Spatiotemporal Control of Type III-A CRISPR-Cas Immunity: Coupling DNA Degradation with the Target RNA Recognition.
Staphylococcus aureus Nuc2 is a functional, surface-attached extracellular nuclease.
Temporal association of the herpes simplex virus genome with histone proteins during a lytic infection.
The "Bridge" in the Epstein-Barr Virus Alkaline Exonuclease Protein BGLF5 Contributes to Shutoff Activity during Productive Infection.
The CRISPR ancillary effector Can2 is a dual-specificity nuclease potentiating type III CRISPR defence.
The DNase Activity of KSHV SOX Protein Serves an Important Role in Viral Genome Processing During Lytic Replication.
The Mga Regulon but Not Deoxyribonuclease Sda1 of Invasive M1T1 Group A Streptococcus Contributes to In Vivo Selection of CovRS Mutations and Resistance to Innate Immune Killing Mechanisms.
Time course of serum nuclease activity in mice infected with plasmodium malariae.
Unusual recovery of animal staphylococci from septic wounds of hospital patients in Ile-Ife, Nigeria.
UV inactivation of adenovirus type 41 measured by cell culture mRNA RT-PCR.
Visualization of extracellular DNA released during border cell separation from the root cap.
[Comparison of histology, immunohistochemistry, RT-PCR, in situ hybridization, and in situ RT-PCR for demonstration of hepatitis C virus in paraffin-embedded liver biopsies]
[Incidence and diagnostic significance of reactive syphilis antibodies in systemic lupus erythematodes and other immunologic diseases]
[Nuclease activity of the recombinant plancitoxin-1-like proteins with mutations in the active site from Trichinella spiralis].
[Role of nucleases in the origination of chromosomal disorders in virus-infected cells]
[Serum DNAse activity induction as a mechanism of infection resistance in man and animals]
[Serum nucleases as nonspecific antiviral factors and their role in artificial anti-influenza immunity]
[Socioeconomic evaluation of the effect of rhDNase on the cost of treating infections of the respiratory tract in patients with cystic fibrosis]
Infectious Mononucleosis
Frequency and levels of antibodies to Epstein-Barr virus-specific DNase are elevated in patients with nasopharyngeal carcinoma.
High-level expression of the Epstein-Barr virus alkaline deoxyribonuclease using a recombinant baculovirus: application to the diagnosis of nasopharyngeal carcinoma.
Influenza, Human
Comparison of nucleic acid extraction methods for next-generation sequencing of avian influenza A virus from ferret respiratory samples.
[Serum nucleases as nonspecific antiviral factors and their role in artificial anti-influenza immunity]
Kartagener Syndrome
Clinical benefit from nebulized human recombinant DNase in Kartagener's syndrome.
Leg Ulcer
Blow fly Lucilia sericata nuclease digests DNA associated with wound slough/eschar and with Pseudomonas aeruginosa biofilm.
The safety and efficacy of a proteolytic ointment in the treatment of chronic ulcers of the lower extremity.
Lemierre Syndrome
A case of Lemierre's syndrome with septic shock and complicated parapneumonic effusions requiring intrapleural fibrinolysis.
Leukemia
Cytotoxic activity of 2-aminomethylene-3(2H)-benzofuranones against human oral tumor cell lines.
DNase I hypersensitivity patterns of the serglycin proteoglycan gene in resting and phorbol 12-myristate 13-acetate-stimulated human erythroleukemia (HEL), CHRF 288-11, and HL-60 cells compared with neutrophils and human umbilical vein endothelial cells.
Mapping of DNase I-hypersensitive sites in the 5' and 3' long terminal repeats of integrated moloney murine leukemia virus proviral DNA.
Mapping of DNase I-hypersensitive sites in the upstream DNA of human embryonic epsilon-globin gene in K562 leukemia cells.
Retrovirus integration and chromatin structure: Moloney murine leukemia proviral integration sites map near DNase I-hypersensitive sites.
Significance of DNase I-hypersensitive sites in the long terminal repeats of a Moloney murine leukemia virus vector.
[Consideration on the classification and therapy of acute leukemia of infants. II. Hydrolysis of leukemia erythrocytes by DNase and RNase. With special reference to normal or leukemic bone marrow cells]
[Increases in the activity of lysosomal DNAase in mouse liver during the development of Friend's viral leukemia]
Leukemia, Erythroblastic, Acute
Detection of two tissue-specific DNA-binding proteins with affinity for sites in the mouse beta-globin intervening sequence 2.
DNA ligase and DNase activities in mouse erythroleukemia cells during dimethyl sulfoxide-induced differentiation.
DNase I hypersensitivity patterns of the serglycin proteoglycan gene in resting and phorbol 12-myristate 13-acetate-stimulated human erythroleukemia (HEL), CHRF 288-11, and HL-60 cells compared with neutrophils and human umbilical vein endothelial cells.
High-resolution analysis of the human gamma-globin gene promoter in K562 erythroleukemia cell chromatin.
Preferential cross-linking of matrix-attachment region (MAR) containing DNA fragments to the isolated nuclear matrix by ionizing radiation.
Promoter regulatory elements and DNase I-hypersensitive sites involved in serglycin proteoglycan gene expression in human erythroleukemia, CHRF 288-11, and HL-60 cells.
Protein-DNA interactions in the epsilon-globin gene silencer.
Vesicular stomatitis virus M protein in the nuclei of infected cells.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Double-stranded RNA excess in hematologic diseases: clinical implications.
Leukemia, Myeloid
Nuclear translocation of DNase II and acid phosphatase during radiation-induced apoptosis in HL60 cells.
Undermethylation and DNase I hypersensitivity of myeloperoxidase gene in HL-60 cells before and after differentiation.
Leukemia, Myeloid, Acute
A cell-type deconvolution meta-analysis of whole blood EWAS reveals lineage-specific smoking-associated DNA methylation changes.
Double-stranded RNA excess in hematologic diseases: clinical implications.
Leukoplakia
Immunological studies on the Epstein-Barr virus encoded alkaline deoxyribonuclease found in virus-producing lymphoblastoid cells.
Liver Abscess
Culture-independent analysis of liver abscess using nanopore sequencing.
Liver Cirrhosis
The Role of IFN?-Producing Th1 Cells in a Type I IFN-Independent Murine Model of Autoinflammation Resulting from DNase II-Deficiency.
Liver Neoplasms
DNase is a prognostic marker in liver cancer patients receiving transarterial chemoembolization therapy.
Predictive value of immunogenic cell death biomarkers HMGB1, sRAGE, and DNase in liver cancer patients receiving transarterial chemoembolization therapy.
Liver Neoplasms, Experimental
Tissue-specific changes in chromatin structure of the rat aldolase B locus.
Lung Abscess
Endobronchial Instillation of DNase to Facilitate Bronchoscopic Drainage of a Lung Abscess.
Lung Diseases
Actin-Resistant DNase1L2 as a Potential Therapeutics for CF Lung Disease.
Airway surface liquid contains endogenous DNase activity which can be activated by exogenous magnesium.
An update on bronchiectasis.
Clinical benefit from nebulized human recombinant DNase in Kartagener's syndrome.
Clinical studies of rhDNase in moderately and severely affected patients with cystic fibrosis--an overview.
Cystic fibrosis.
Effect of DNase on exercise capacity in cystic fibrosis.
Effects of 12-week administration of dornase alfa in patients with advanced cystic fibrosis lung disease. Pulmozyme Study Group.
Matrix metalloproteases in BAL fluid of patients with cystic fibrosis and their modulation by treatment with dornase alpha.
Multicenter, open-label study of recombinant human DNase in cystic fibrosis patients with moderate lung disease. DNase International Study Group.
Nebulised hypertonic saline for cystic fibrosis.
Neutrophil Extracellular Traps in Pulmonary Diseases: Too Much of a Good Thing?
Lung Injury
Mitochondrial DNA damage associated molecular patterns in ventilator-associated pneumonia: Prevention and reversal by intratracheal DNase I.
Neutrophil Extracellular Traps Are Pathogenic in Ventilator-Induced Lung Injury and Partially Dependent on TLR4.
Lung Neoplasms
Bronchoscopic instillation of DNase to manage refractory lobar atelectasis in a lung cancer patient.
Cladribine enhances apoptotic cell death in lung carcinoma cells over-expressing DNase ?.
Systemic lupus erythematosus and DNA antibodies in pleural effusions.
Lupus Erythematosus, Cutaneous
Role of soluble and cell surface molecules in the pathogenesis of autoimmune skin diseases.
Lupus Erythematosus, Systemic
Antigenic structure of DNA: relatively high inhibitory activity of di- and trideoxyribonucleotide derived from DNase digest on the interaction of thermally denatured DNA with systemic lupus erythematosus sera.
Assessment of Deoxyribonuclease Activity in Serum Samples of Patients With Systemic Lupus Erythematosus: Fluorescence-Based Method Versus ELISA.
Associations of DNase IV polymorphisms with autoantibodies in patients with systemic lupus erythematosus.
Deoxyribonucleases and Their Applications in Biomedicine.
dsDNA-, nucleohistone- and DNASE I-reactive T lymphocytes in patients affected by systemic lupus erythematosus: correlation with clinical disease activity.
Failure to detect circulating DNA--anti-DNA complexes by four radioimmunological methods in patients with systemic lupus erythematosus.
Formation of different abzymes in autoimmune-prone MRL-lpr/lpr mice is associated with changes in colony formation of haematopoietic progenitors.
Interaction of fibronectin with DNA/anti-DNA complexes from systemic lupus erythematosus: role of activated complement Cl in modulation of the interactions.
Neutrophil Extracellular Traps in the Autoimmunity Context.
Novel DNA-protein complex and a large DNA in SLE cryoprecipitates.
Systemic lupus erythematosus: molecular cloning and analysis of recombinant DNase monoclonal ? light chain NGK-1.
Systemic lupus erythematosus: Molecular cloning of fourteen recombinant DNase monoclonal kappa light chains with different catalytic properties.
Systemic lupus erythematosus: molecular cloning of several recombinant DNase monoclonal kappa light chains with different catalytic properties.
The treatment of systemic lupus erythematosus (SLE) in NZB/W F1 hybrid mice; studies with recombinant murine DNase and with dexamethasone.
[Extracorporeal treatment of nucleoprotein disposal disorders using the systemic lupus erythematosus model: evaluation of efficacy and safety in a short-term simulated experiment].
Lupus Nephritis
The treatment of systemic lupus erythematosus (SLE) in NZB/W F1 hybrid mice; studies with recombinant murine DNase and with dexamethasone.
[Circulating polynucleotide and DNA antibody content and the DNase activity of the blood in clinical and experimental lupus nephritis]
Lymphadenitis
Involvement of DNase gamma in apoptotic DNA fragmentation in histiocytic necrotizing lymphadenitis.
Lymphadenopathy
Involvement of DNase gamma in apoptotic DNA fragmentation in histiocytic necrotizing lymphadenitis.
Lymphoma
Highly sensitive nuclease assays based on chemically modified DNA or RNA.
Molecular characterization of circulating EBV DNA in the plasma of nasopharyngeal carcinoma and lymphoma patients.
Poly (ADP-ribose) metabolism in alkylated mouse L5178Y cells.
Synthesis and antiproliferative activity of benzophenone tagged pyridine analogues towards activation of caspase activated DNase mediated nuclear fragmentation in Dalton's lymphoma.
Synthesis of novel morpholine conjugated benzophenone analogues and evaluation of antagonistic role against neoplastic development.
Lymphoma, B-Cell
Inducible transcription of the unrearranged kappa constant region locus is a common feature of pre-B cells and does not require DNA or protein synthesis.
Streptozotocin-induced diabetic cardiomyopathy in rats: ameliorative effect of PIPERINE via Bcl2, Bax/Bcl2, and caspase-3 pathways.
Malaria
CXCR4 and MIF are required for neutrophil extracellular trap release triggered by Plasmodium-infected erythrocytes.
Expression and functional analysis of the TatD-like DNase of Plasmodium knowlesi.
Plasmodium TatD-Like DNase Antibodies Blocked Parasite Development in the Mosquito Gut.
The TatD-like DNase of Plasmodium is a virulence factor and a potential malaria vaccine candidate.
Malaria, Cerebral
CXCR4 and MIF are required for neutrophil extracellular trap release triggered by Plasmodium-infected erythrocytes.
Mastitis
A simple identification scheme for coagulase negative staphylococci from bovine mastitis.
Capsular Type, Sequence Type and Microbial Resistance Factors Impact on DNase Activity of Streptococcus agalactiae Strains from Human and Bovine Origin.
Screening method for Staphylococcus aureus identification in subclinical bovine mastitis from dairy farms.
[Validation of DNAse reaction for identification of Staphylococcus aureus strains in routine mastitis diagnosis]
Meconium Ileus
Cystic fibrosis colonopathy.
Melanoma
Active immunotherapy of human melanoma exploiting the immunopotentiating effects of cyclophosphamide.
Cutting edge: AIM2 and endosomal TLRs differentially regulate arthritis and autoantibody production in DNase II-deficient mice.
Immunoregulating properties of peptides related to tumor rejection antigens: effect on human monocytes and natural killer cells.
Meningitis
Role of Bacterial and Host DNases on Host-Pathogen Interaction during Streptococcus suis Meningitis.
Meningitis, Pneumococcal
DNase Treatment Prevents Cerebrospinal Fluid Block in Early Experimental Pneumococcal Meningitis.
Metrorrhagia
DNase test as a novel approach for the routine screening of Corynebacterium diphtheriae.
Mouth Neoplasms
Highly sensitive nuclease assays based on chemically modified DNA or RNA.
Multiple Myeloma
Double-stranded RNA excess in hematologic diseases: clinical implications.
Multiple Sclerosis
Catalytic heterogeneity of polyclonal DNA-hydrolyzing antibodies from the sera of patients with multiple sclerosis.
DNase hypersensitive sites and association with multiple sclerosis.
Hydrolysis of myelin basic protein by polyclonal catalytic IgGs from the sera of patients with multiple sclerosis.
Mycoplasma Infections
S-phase detection with an antibody to bromodeoxyuridine. Role of DNase pretreatment.
Myocardial Infarction
Coronary Neutrophil Extracellular Trap Burden and DNase Activity in ST-Elevation Acute Coronary Syndrome are Predictors of ST-Segment Resolution and Infarct Size.
Culprit site extracellular DNA and microvascular obstruction in ST-elevation myocardial infarction.
Gelsolin regulates cardiac remodeling after myocardial infarction through DNase I-mediated apoptosis.
Highly sensitive nuclease assays based on chemically modified DNA or RNA.
Mitochondrially targeted Endonuclease III has a powerful anti-infarct effect in an in vivo rat model of myocardial ischemia/reperfusion.
Myocardial Ischemia
Highly sensitive nuclease assays based on chemically modified DNA or RNA.
Neutrophil extracellular traps in ischemia-reperfusion injury-induced myocardial no-reflow: therapeutic potential of DNase-based reperfusion strategy.
Myositis
Mitogenic factor (MF) is the major DNase of serotype M89 Streptococcus pyogenes.
Nasopharyngeal Carcinoma
A prospective study of antibodies to Epstein-Barr virus DNase and viral capsid antigen for prognostication of patients with nasopharyngeal carcinoma.
Activity of DNase associated with replication of Epstein-Barr virus in NPC-204 cells.
Antibodies to Epstein-Barr virus-specific DNase in patients with nasopharyngeal carcinoma and control groups.
Antibody response to Epstein-Barr-virus-specific DNase in 13 patients with nasopharyngeal carcinoma in Taiwan: a retrospective study.
Antibody responses to Epstein-Barr virus-specific DNase in relation to the prognosis of juvenile patients with nasopharyngeal carcinoma.
Antibody to Epstein-Barr virus specific DNase in sera of nasopharyngeal carcinoma and other nine most common cancer patients in Taiwan.
Antibody to Epstein-Barr virus-specific DNase as a marker for field survey of patients with nasopharyngeal carcinoma in Taiwan.
Antibody to Epstein-Barr virus-specific DNase as a marker for the early detection of nasopharyngeal carcinoma.
Antibody to Epstein-Barr virus-specific DNase in patients with nasopharyngeal carcinoma.
Antigenic variation in alkaline deoxyribonuclease induced by three different strains of Epstein-Barr virus.
Detection of EB Virus Gene Fragments in Paraffin-embedded NPC Tissue.
Epstein-Barr virus-specific DNase activity in nonproducer Raji cells after treatment with 12-o-tetradecanoylphorbol-13-acetate and sodium butyrate.
Expression of the DNase encoded by the BGLF5 gene of Epstein-Barr virus in nasopharyngeal carcinoma epithelial cells.
Frequency and levels of antibodies to Epstein-Barr virus-specific DNase are elevated in patients with nasopharyngeal carcinoma.
High-level expression of the Epstein-Barr virus alkaline deoxyribonuclease using a recombinant baculovirus: application to the diagnosis of nasopharyngeal carcinoma.
Immune responses to Epstein-Barr virus lytic proteins in patients with nasopharyngeal carcinoma.
Immunological studies on the Epstein-Barr virus encoded alkaline deoxyribonuclease found in virus-producing lymphoblastoid cells.
Independent effect of EBV and cigarette smoking on nasopharyngeal carcinoma: a 20-year follow-up study on 9,622 males without family history in Taiwan.
Molecular characterization of a cDNA clone encoding the Epstein-Barr virus (EBV) DNase.
Molecular characterization of circulating EBV DNA in the plasma of nasopharyngeal carcinoma and lymphoma patients.
Purification of Epstein-Barr virus associated DNase with affinity chromatography of nasopharyngeal carcinoma patient serum.
Serologic markers of Epstein-Barr virus infection and nasopharyngeal carcinoma in Taiwanese men.
Neoplasm Metastasis
Cancer cells induce metastasis-supporting neutrophil extracellular DNA traps.
Interaction of the Tumor Metastasis Suppressor Nonmetastatic Protein 23 Homologue H1 and Estrogen Receptor {alpha} Alters Estrogen-Responsive Gene Expression.
Metastatic potential of human colorectal carcinomas implanted into nude mice: prediction of clinical outcome in patients operated upon for cure.
SET-ting the stage for life and death.
Neoplasms
A human colon adenocarcinoma xenograft--radiation response, cellular composition, and tumor disaggregation.
A novel approach to immunomodulation of frozen human bone marrow with interleukin-2 for clinical application.
A rapid and sensitive method for kinetic study and activity assay of DNase I in vitro based on a GO-quenched hairpin probe.
A successful liver metastasis model in mice with neuraminidase treated colon 26.
A virus-like agent associated with neurofibromatosis in damselfish.
Alteration of the exDNA profile in blood serum of LLC-bearing mice under the decrease of tumour invasion potential by bovine pancreatic DNase I treatment.
Altered actin organization in an N-methyl-N'-nitro-N-nitrosoguanidine-transformed pulmonary epithelial cell line.
Altered deoxyribonuclease activity in cancer cells and its role in non toxic adjuvant cancer therapy with mixed vitamins C and K3.
An improved filter-disc assay for 3H-DNA and serum deoxyribonucleases.
Analysis of deoxyribonuclease activity by conjugation-free fluorescence polarisation in sub-nanolitre droplets.
Antiangiogenic and proapoptotic activity of a novel glycoprotein from U. indica is mediated by NF-kappaB and Caspase activated DNase in ascites tumor model.
Antibodies to Epstein-Barr virus-specific DNase in patients with nasopharyngeal carcinoma and control groups.
Antibody to Epstein-Barr virus specific DNase in sera of nasopharyngeal carcinoma and other nine most common cancer patients in Taiwan.
Anticancer activity of mycobacterial DNA: effect of formulation as chitosan nanoparticles.
Antitumor activity of deoxyribonucleic acid fraction from Mycobacterium bovis BCG. I. Isolation, physicochemical characterization, and antitumor activity.
Cell cycle arrest and autoschizis in a human bladder carcinoma cell line following Vitamin C and Vitamin K3 treatment.
Cellular distribution of endothelin-1 mRNA in human brain by in situ RT-PCR.
Chemosensitivity testing for human brain tumors.
Chromatin profiling across the human tumour necrosis factor gene locus reveals a complex, cell type-specific landscape with novel regulatory elements.
Circulating DNA and DNase activity in human blood.
Circulating nucleosomes and biomarkers of immunogenic cell death as predictive and prognostic markers in cancer patients undergoing cytotoxic therapy.
Confocal microscopy of genome exposure in normal, cancer, and reverse-transformed cells.
Correlation between serum and tissue deoxyribonuclease levels in breast cancer patients.
Cytotoxic activity of 2-aminomethylene-3(2H)-benzofuranones against human oral tumor cell lines.
Deoxyribonuclease activity and circulating DNA concentration in blood plasma of patients with prostate tumors.
Deoxyribonuclease-hypersensitive sites in the glycoprotein hormone alpha-subunit gene from trophoblastic and nontrophoblastic human tumor cell lines: correlation with expression and effect of chemical inducers.
Detection of estrogen receptors with monoclonal antibodies in routinely processed formalin-fixed paraffin sections of breast carcinoma. Use of DNase pretreatment to enhance sensitivity of the reaction.
Differential DNA repair underlies mutation hotspots at active promoters in cancer genomes.
DNA released from neutrophil extracellular traps (NETs) activates pancreatic stellate cells and enhances pancreatic tumor growth.
DNase I inhibitions in tumors of different metastasizing capacities: a possible index of invasiveness.
DNase I-assisted 2'-O-methyl molecular beacon for amplified detection of tumor exosomal microRNA-21.
DNase I-sensitive sites within the nuclear architecture visualized by immunoelectron microscopy.
Effect of deoxyribonuclease on adriamycin-polynucleotide complexes.
Effect of enzymatic disaggregation on proliferation of human tumor cells in soft agar.
Epstein-Barr virus BRLF1 induces genomic instability and progressive malignancy in nasopharyngeal carcinoma cells.
Evaluation of cell subpopulations isolated from human tumor xenografts by centrifugal elutriation.
Expression of the DNase encoded by the BGLF5 gene of Epstein-Barr virus in nasopharyngeal carcinoma epithelial cells.
Extracellular RNA Liberates Tumor Necrosis Factor-? to Promote Tumor Cell Trafficking and Progression.
Foreign body sarcoma: effects of foreign DNA, beta-carotene and paprika applied to the implant surface.
Frequency and levels of antibodies to Epstein-Barr virus-specific DNase are elevated in patients with nasopharyngeal carcinoma.
Generation of Orthotopic Pancreatic Tumors and Ex vivo Characterization of Tumor-Infiltrating T Cell Cytotoxicity.
Growth potential of human colorectal carcinomas in nude mice: association with the preoperative serum concentration of carcinoembryonic antigen in patients.
Histone deacetylase activity represses gamma interferon-inducible HLA-DR gene expression following the establishment of a DNase I-hypersensitive chromatin conformation.
Identification and characterization of a DNase induced by Epstein-Barr virus.
In vitro BrdUrd incorporation of colorectal tumour tissue.
In vitro demonstration of in situ autologous tumour-cell cytotoxicity in MSV-induced tumours in A/SN mice.
In vitro expansion and analysis of T lymphocyte microcultures obtained from the vaccination sites of cancer patients undergoing active specific immunization with autologous Newcastle-disease-virus-modified tumour cells.
In vivo reactivation of DNases in implanted human prostate tumors after administration of a vitamin C/K(3) combination.
Increased uracil-DNA glycosylase, AP-DNA binding protein and deoxyribonuclease activities in tumor and SV40-transformed cell lines of human origin.
Inhibition of DNA synthesis by a small-cell lung carcinoma-derived protein.
Lactoferrin is the major deoxyribonuclease of human milk.
Local delivery of a recombinant adeno-associated vector containing a tumor necrosis factor-{alpha} antagonist gene in inflammatory arthritis: a phase 1 dose-escalation safety and tolerability study.
Mechanism of inhibition of ascites tumor growth in mice by curcumin is mediated by NF-kB and caspase activated DNase.
Metastatic potential of human colorectal carcinomas implanted into nude mice: prediction of clinical outcome in patients operated upon for cure.
Molecular character of the recombinant antitumor lectin from the edible mushroom Agrocybe aegerita.
Neutrophil Extracellular Traps Drive Mitochondrial Homeostasis in Tumors to Augment Growth.
Non-toxic potentiation of cancer chemotherapy by combined C and K3 vitamin pre-treatment.
Nuclear war: the granzyme A-bomb.
Overexpression of lncRNA TATDN1 Promotes Cancer Cell Proliferation in Triple Negative Breast Cancer by Regulating miR-26b Methylation.
Pathways- and epigenetic-based assessment of relative immune infiltration in various types of solid tumors.
Prediction of response to neoadjuvant chemotherapy in breast cancer patients by circulating apoptotic biomarkers nucleosomes, DNAse, cytokeratin-18 fragments and survivin.
Profiling of cancer cells using protein microarrays: discovery of novel radiation-regulated proteins.
Radiolabeled DNase, a potential indicator for noninvasive detection of tissue damage.
Recovery of cell subpopulations from human tumour xenografts following dissociation with different enzymes.
Reduced neutral DNase activity in the urine of children after cytostatic therapy.
Regulation of the innate immune response by threonine-phosphatase of Eyes absent.
Response of an in vivo-in vitro tumour to X-rays and cytotoxic drugs: effect of tumour disaggregation method on cell survival.
Reversibility of acid and alkaline deoxyribonuclease deficiency in malignant tumor cells.
RNA inhibits estrogen receptor binding to DNA.
SET-ting the stage for life and death.
Six catalytic activities and cytotoxicity of immunoglobulin G and secretory immunoglobulin A from human milk.
South African Herbal Extracts as Potential Chemopreventive Agents: Screening for Anticancer Splicing Activity.
Streptozotocin-induced diabetic cardiomyopathy in rats: ameliorative effect of PIPERINE via Bcl2, Bax/Bcl2, and caspase-3 pathways.
Synthesis and antiproliferative activity of benzophenone tagged pyridine analogues towards activation of caspase activated DNase mediated nuclear fragmentation in Dalton's lymphoma.
Synthesis and application of a non-viral gene delivery system for immunogene therapy of cancer.
The C1q binding test for soluble immune complexes: clinical correlations obtained in patients with cancer.
The DNase Activity of KSHV SOX Protein Serves an Important Role in Viral Genome Processing During Lytic Replication.
The Effect of Genomic DNA Contamination on the Detection of Circulating Long Non-Coding RNAs: The Paradigm of MALAT1.
The effects of biofilms on tumor progression in a 3D cancer-biofilm microfluidic model.
The microtiter SDI test is more advantageous than the SDI test for assessing the chemosensitivity of human tumor cells.
The mitochondrial uncoupling protein gene in brown fat: correlation between DNase I hypersensitivity and expression in transgenic mice.
The position and length of the steroid-dependent hypersensitive region in the mouse mammary tumor virus long terminal repeat are invariant despite multiple nucleosome B frames.
The role and potential mechanisms of LncRNA-TATDN1 on metastasis and invasion of non-small cell lung cancer.
Tumor suppressor NM23-H1 is a granzyme A-activated DNase during CTL-mediated apoptosis, and the nucleosome assembly protein SET is its inhibitor.
Two-dimensional electrophoresis of proteins in tumours of the lung.
Variability in glucose transporter-1 levels and hexokinase activity in human melanoma.
ZnO Nanoparticles Protect RNA from Degradation Better than DNA.
[Dynamic of DNAse activity induction in serum of normal animals after heterogeneous DNA injection and in hereditary pathology]
[In vitro chemosensitivity testing with the human tumor stem cell assay (HTSCA) in breast cancer]
[Ol'ha Petrivna Chepinoha--a founder of investigations of nucleic acids in biochemistry in Ukraine. To the 100th anniversary of birthday, 1.07.1907--27.04.1983]
Nephritis
Effect of coexistent serum DNA on qualitative properties of anti-DNA antibodies.
Heterogeneity and clinical significance of glomerular-binding antibodies in systemic lupus erythematosus.
Nephrolithiasis
Effects of Nephrolithiasis on Serum DNase (Deoxyribonuclease I and II) Activity and E3 SUMO-Protein Ligase NSE2 (NSMCE2) in Malaysian Individuals.
Nervous System Diseases
An altered apurinic DNA endonuclease activity in group A and group D xeroderma pigmentosum fibroblasts.
Neuroblastoma
Differential DNases are selectively used in neuronal apoptosis depending on the differentiation state.
The Acetyl Mimicking Mutation, K274Q in Tau, Enhances the Metal Binding Affinity of Tau and Reduces the Ability of Tau to Protect DNA.
Oligospermia
HT-COMET: a novel automated approach for high throughput assessment of human sperm chromatin quality.
Pancreatic Neoplasms
Characterization of human deoxyribonuclease I gene (DNASE1) promoters reveals the utilization of two transcription-starting exons and the involvement of Sp1 in its transcriptional regulation.
Circulating nucleosomes and immunogenic cell death markers HMGB1, sRAGE and DNAse in patients with advanced pancreatic cancer undergoing chemotherapy.
Clinical investigation of serum deoxyribonuclease: II. Clinical studies of serum deoxyribonuclease activity in pancreatic disease.
Serum deoxyribonuclease and ribonuclease in pancreatic cancer and chronic pancreatitis.
Pancreatitis
Relationship between pancreatic enzymes and pathological changes in the pancreas in acute pancreatitis. The significance of determination of serum deoxyribonuclease.
Serum DNase activity after experimental, acute hemorrhagic-necrotizing pancreatitis in dogs: detection of a serum DNase isoenzyme.
Pancreatitis, Chronic
Clinical investigation of serum deoxyribonuclease: II. Clinical studies of serum deoxyribonuclease activity in pancreatic disease.
Serum deoxyribonuclease and ribonuclease in pancreatic cancer and chronic pancreatitis.
Papillomavirus Infections
Influence of human papillomavirus on DNA ploidy determination in genital condylomas.
Parakeratosis
AKT1-mediated Lamin A/C degradation is required for nuclear degradation and normal epidermal terminal differentiation.
Survey of single-nucleotide polymorphisms in the gene encoding human deoxyribonuclease I-like 2 producing loss of function potentially implicated in the pathogenesis of parakeratosis.
Parasitemia
CXCR4 and MIF are required for neutrophil extracellular trap release triggered by Plasmodium-infected erythrocytes.
Paratuberculosis
Unexpected detection of DNA by nucleic acid sequence-based amplification technique.
Parkinson Disease
Studies on genomic DNA topology and stability in brain regions of Parkinson's disease.
Periodontal Diseases
Extracellular deoxyribonuclease production by periodontal bacteria.
Periodontitis
Extracellular deoxyribonuclease production by periodontal bacteria.
Peritonitis
Preclinical Assessment of Adjunctive tPA and DNase for Peritoneal Dialysis Associated Peritonitis.
Persistent Infection
DNase Inhibits Gardnerella vaginalis Biofilms In Vitro and In Vivo.
Pharyngitis
Group A Streptococcus establishes pharynx infection by degrading the deoxyribonucleic acid of neutrophil extracellular traps.
Pheochromocytoma
Presence of DNase gamma-like endonuclease in nuclei of neuronal differentiated PC12 cells.
The 3' flanking region of the human tyrosine hydroxylase gene directs reporter gene expression in peripheral neuroendocrine tissues.
Pituitary Neoplasms
Chromatin structure, transcription, and methylation of the prolactin gene domain in pituitary tumors of Fischer 344 rats.
The prolactin gene hypersensitive sites are present early in development and are not induced by estrogen administration.
Plasmacytoma
A New Hypersensitive Site, HS10, and the Enhancers, E3' and Ed, Differentially Regulate Ig? Gene Expression.
Methylation status and DNase I sensitivity of immunoglobulin genes: changes associated with rearrangement.
The immunoglobulin heavy chain locus control region increases histone acetylation along linked c-myc genes.
Pleural Effusion
Extended Dwell Time Improves Results of Fibrinolytic Therapy for Complex Pleural Effusions.
Intrapleural heparin or heparin combined with human recombinant DNase is not effective in the treatment of empyema in a rabbit model.
Safety and Efficacy of Tissue Plasminogen Activator and DNase for Complicated Pleural Effusions Secondary to Abdominal Pathology.
Systemic lupus erythematosus and DNA antibodies in pleural effusions.
Pneumonia
Rethinking the Doses of Tissue Plasminogen Activator and Deoxyribonuclease Administrated Concurrently for Intrapleural Therapy for Complicated Pleural Effusion and Empyema.
Pre-Eclampsia
Deoxyribonuclease activity in plasma of pregnant women and experimental animals.
Deoxyribonuclease activity negative correlates with extracellular DNA in uncomplicated singleton pregnancies in the third trimester.
Role of fetal DNA in preeclampsia (review).
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Double-stranded RNA excess in hematologic diseases: clinical implications.
Pregnancy Complications
Deoxyribonuclease activity negative correlates with extracellular DNA in uncomplicated singleton pregnancies in the third trimester.
Premature Birth
Deoxyribonuclease activity negative correlates with extracellular DNA in uncomplicated singleton pregnancies in the third trimester.
Prostatic Neoplasms
Factorial Design and Development of Solid Lipid Nanoparticles (SLN) for Gene Delivery.
In vivo reactivation of DNases in implanted human prostate tumors after administration of a vitamin C/K(3) combination.
Prostatitis
Deoxyribonuclease activity and circulating DNA concentration in blood plasma of patients with prostate tumors.
Proteinuria
Deoxyribonuclease-inhibitory antibodies in systemic lupus erythematosus.
Does rat fetal DNA induce preeclampsia in pregnant rats?
Pseudomonas Infections
Aerosol therapy in patients with cystic fibrosis.
Pseudorabies
Identification of a DNA-binding domain and an active-site residue of pseudorabies virus DNase.
Pseudorabies virus DNA-binding protein stimulates the exonuclease activity and regulates the processivity of pseudorabies virus DNase.
Recombinant pseudorabies virus DNase exhibits a RecBCD-like catalytic function.
Psoriasis
[Distribution of DNase and RNase in psoriasis and their changes following PUVA--a study using immunohistochemical methods]
[Distribution of nuclear DNase in psoriasis vulgaris and its changes after several therapies--a study of immunohistochemistry]
Pulmonary Atelectasis
Angioedema Associated With Nebulized Recombinant Human DNase in a Preterm Infant: Case Report.
Bronchoscopic instillation of DNase to manage refractory lobar atelectasis in a lung cancer patient.
Bronchoscopically administered recombinant human DNase for lobar atelectasis in cystic fibrosis.
Comparing the efficacy of nebulizer recombinant human DNase and hypertonic saline as monotherapy and combined treatment in the treatment of persistent atelectasis in mechanically ventilated newborns.
DNase and atelectasis in non-cystic fibrosis pediatric patients.
DNase treatment for atelectasis in infants with severe respiratory syncytial virus bronchiolitis.
Efficacy and safety of nebulized recombinant human DNase as rescue treatment for persistent atelectasis in newborns: case-series.
Endotracheal DNase for atelectasis in ventilated neonates.
Nebulized Hypertonic Saline and Recombinant Human DNase In The Treatment Of Pulmonary Atelectasis In Newborns.
Recombinant human DNase in management of lobar atelectasis due to retained secretions.
Rescue use of DNase in critical lung atelectasis and mucus retention in premature neonates.
Resolution of chronic atelectasis in a child with asthma after aerosolized recombinant human DNase.
Resolution of mucus plugging and atelectasis after intratracheal rhDNase therapy in a mechanically ventilated child with refractory status asthmaticus.
Resolution of recurrent atelectasis in spinal cord injury patients with administration of recombinant human DNase.
Safety of endotracheal rh DNAse (Pulmozyme) for treatment of pulmonary atelectasis in mechanically ventilated children.
Treatment of lobar atelectasis with bronchoscopically administered recombinant human deoxyribonuclease in cystic fibrosis?
Use of recombinant human DNase in a premature infant with recurrent atelectasis.
Pulmonary Disease, Chronic Obstructive
Bronchoscopically administered recombinant human DNase for lobar atelectasis in cystic fibrosis.
Quadriplegia
Bronchoscopically administered recombinant human DNase for lobar atelectasis in cystic fibrosis.
Renal Insufficiency
Deoxyribonuclease activity in T and B lymphocytes of haemodialysed patients with uraemia.
Respiratory Tract Infections
Effect of aerosolized rhDNase (Pulmozyme(R)) on pulmonary colonization in patients with cystic fibrosis.
Effects of recombinant human DNase therapy on healthcare use and costs in patients with cystic fibrosis.
Recombinant human DNase in children with airway malacia and lower respiratory tract infection.
Rheumatic Diseases
Deoxyribonuclease activity of polyclonal IgGs: a putative serological marker in patients with spondyloarthritides.
Rhinitis
Therapeutic approaches to mucus hypersecretion.
Sarcoma
Immunological studies on Yoshida sarcoma cells. I. The effect of heterologous anti-Yoshida sarcoma cell antibodies on the lysosomal acid DNase of sarcoma cells.
Inflammatory cells in solid murine neoplasms. II. Cell types found throughout the course of Moloney sarcoma regression or progression.
Sarcoma, Yoshida
Immunological studies on Yoshida sarcoma cells. I. The effect of heterologous anti-Yoshida sarcoma cell antibodies on the lysosomal acid DNase of sarcoma cells.
Scarlet Fever
Molecular characterization of the 2011 Hong Kong scarlet fever outbreak.
Prophage exotoxins enhance colonization fitness in epidemic scarlet fever-causing Streptococcus pyogenes.
Scleroderma, Diffuse
[Anti-proteinase 3 antibodies in diffuse systemic sclerosis (SSc) with normotensive renal impairment: is it suggestive for an overlapping between SSc and idiopathic vasculitis? ]
Scleroderma, Limited
[Anti-proteinase 3 antibodies in diffuse systemic sclerosis (SSc) with normotensive renal impairment: is it suggestive for an overlapping between SSc and idiopathic vasculitis? ]
Sepsis
Cost-effectiveness of intrapleural use of tissue plasminogen activator and DNase in pleural infection: evidence from the MIST2 randomised controlled trial.
Delayed but not Early Treatment with DNase Reduces Organ Damage and Improves Outcome in a Murine Model of Sepsis.
Early Dynamics of Plasma DNA in a Mouse Model of Sepsis.
Exogenous deoxyribonuclease has a protective effect in a mouse model of sepsis.
Management of Pleural Infection.
Neutrophil extracellular trap-microparticle complexes enhance thrombin generation via the intrinsic pathway of coagulation in mice.
[Biological properties of opportunistic enterobacteria isolated from the blood of patients]
Shock, Septic
Characteristics of Staphylococcus aureus isolated from peracute, acute and chronic bovine mastitis.
Spinal Cord Injuries
Free circulating DNA and DNase activity in the ejaculates of men with spinal cord injury.
Resolution of recurrent atelectasis in spinal cord injury patients with administration of recombinant human DNase.
Spondylitis
Deoxyribonuclease activity of polyclonal IgGs: a putative serological marker in patients with spondyloarthritides.
Spondylitis, Ankylosing
Deoxyribonuclease activity of polyclonal IgGs: a putative serological marker in patients with spondyloarthritides.
ST Elevation Myocardial Infarction
Culprit site extracellular DNA and microvascular obstruction in ST-elevation myocardial infarction.
Deoxyribonuclease 1 Q222R single nucleotide polymorphism and long-term mortality after acute myocardial infarction.
Starvation
Agrobacterium tumefaciens Deploys a Versatile Antibacterial Strategy To Increase Its Competitiveness.
Identification of neutral and acidic deoxyribonuclease activities in Tetrahymena thermophila life stages.
Nucleic acids and related enzymes. Secretion of four alkaline DNases by plasmodia of Physarum polycephalum.
The chromatin structure of Saccharomyces cerevisiae autonomously replicating sequences changes during the cell division cycle.
The ploidy of Vibrio cholerae is variable and is influenced by growth phase and nutrient levels.
Thyroid hormone and dietary carbohydrate interact to regulate rat liver S14 gene transcription and chromatin structure.
Status Asthmaticus
Bronchoscopically administered recombinant human DNase for lobar atelectasis in cystic fibrosis.
Human recombinant DNase for mucus plugging in status asthmaticus.
Resolution of mucus plugging and atelectasis after intratracheal rhDNase therapy in a mechanically ventilated child with refractory status asthmaticus.
Stomach Neoplasms
Circulating DNA and DNase activity in human blood.
Highly sensitive nuclease assays based on chemically modified DNA or RNA.
Streptococcal Infections
DNase Sda1 provides selection pressure for a switch to invasive group A streptococcal infection.
Stroke
Neutrophil extracellular traps promote tPA-induced brain hemorrhage via cGAS in mice with stroke.
Superinfection
Chromatin structure of simian virus 40-pBR322 recombinant plasmids in COS-1 cells.
Synovitis
Deoxyribonuclease activity of polyclonal IgGs: a putative serological marker in patients with spondyloarthritides.
Teratocarcinoma
Negative and positive regulation by a short segment in the 5'-flanking region of the human cytomegalovirus major immediate-early gene.
Thromboinflammation
Extracellular DNA-A Danger Signal Triggering Immunothrombosis.
Tissue Factor-Enriched Neutrophil Extracellular Traps Promote Immunothrombosis and Disease Progression in Sepsis-Induced Lung Injury.
Thrombosis
Arterial thrombosis is accelerated in histidine-rich glycoprotein deficient mice.
Coronary Neutrophil Extracellular Trap Burden and DNase Activity in ST-Elevation Acute Coronary Syndrome are Predictors of ST-Segment Resolution and Infarct Size.
Dysregulation of the actin scavenging system and inhibition of DNase activity following severe thermal injury.
Extracellular DNA traps promote thrombosis.
In Vivo Role of Neutrophil Extracellular Traps in Antiphospholipid Antibody-Mediated Venous Thrombosis.
Neutrophil accumulation and NET release contribute to thrombosis in HIT.
Neutrophil Extracellular Traps Induce Intestinal Damage and Thrombotic Tendency in Inflammatory Bowel Disease.
Thyroid Diseases
A novel mutation in the DNASE1 gene is related with protein instability and decreased enzyme activity in thyroid autoimmunity.
Thyroiditis
Comparison of the Level of DNA-Hydrolyzing Polyclonal IgG Antibodies in Sera of Patients with Hashimoto's Thyroiditis and Nontoxic Nodal Goiter.
Effect of different drugs on the level of DNA-hydrolyzing polyclonal IgG antibodies in sera of patients with Hashimoto's thyroiditis and nontoxic nodal goiter.
Thyroiditis, Autoimmune
Dynamics of antibody nuclease activity in blood of women during pregnancy and lactation.
Tinea
[Exoenzymes of dermatophytes isolated from acute and chronic tinea]
Tuberculosis
Staphylococcus aureus nuclease is a useful secretion reporter for mycobacteria.
Tuberculosis, Pleural
Intrapleural alteplase and DNase for complex tuberculous pleurisy: a medical approach.
Vaccinia
A vaccinia virus DNase preparation which cross-links superhelical DNA.
Behaviour of DNase and RNase in the chorioallantoic membranes of chick embryos infected with vaccinia virus and herpes.
Expression analysis of recombinant herpes simplex virus type 1 DNase.
In situ assay of poxvirus-induced and virion-contained deoxyribonucleases in DNA polyacrylamide gels.
Oscillating probe for dual detection of 5'PO4 and 5'OH DNA breaks in tissue sections.
The assay, purification and properties of vaccinia virus-induced uncoating protein.
Vaginosis, Bacterial
DNase Inhibits Gardnerella vaginalis Biofilms In Vitro and In Vivo.
Vasculitis
Epigenomic functional characterization of genetic susceptibility variants in systemic vasculitis.
Vesicular Stomatitis
Using Pulmozyme DNase treatment in lentiviral vector production.
Virus Diseases
Induction of thymidine kinase and DNase in varicella-zoster virus-infected cells and kinetic properties of the virus-induced thymidine kinase.
Time course of serum nuclease activity in mice infected with plasmodium malariae.
Warts
Genome-Wide CpG Island Methylation Profiles of Cutaneous Skin with and without HPV Infection.
Werner Syndrome
Biochemical mechanisms of chromosomal translocations resulting from DNA double-strand breaks.