Information on EC 2.6.1.63 - kynurenine-glyoxylate transaminase

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EC Tree
     2 Transferases
         2.6 Transferring nitrogenous groups
             2.6.1 Transaminases
                2.6.1.63 kynurenine-glyoxylate transaminase
IUBMB Comments
This enzyme, characterized from animals, belongs to a family of aminotransferases some members of which can use other amino acceptors (cf. EC 2.6.1.7, kynurenine---oxoglutarate transaminase). The products, 4-(2-aminophenyl)-2,4-dioxobutanoate and 4-(2-amino-3-hydroxyphenyl)-2,4-dioxobutanoate, are converted to kynurenate and xanthurenate, respectively, by spontaneous reactions.
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Word Map
The enzyme appears in viruses and cellular organisms
Synonyms
3-HKT, 3-hydroxykynurenine transaminase, aminotransferase, kynurenine-glyoxylate, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
L-kynurenine + glyoxylate = 4-(2-aminophenyl)-2,4-dioxobutanoate + glycine
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acts, more slowly, on L-phenylalanine, L-histidine and L-tyrosine
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