Information on EC 2.4.1.301 - 2'-deamino-2'-hydroxyneamine 1-alpha-D-kanosaminyltransferase

for references in articles please use BRENDA:EC2.4.1.301
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IUBMB Comments
Involved in the biosynthetic pathway of kanamycins. The enzyme characterized from the bacterium Streptomyces kanamyceticus can also accept UDP-alpha-D-glucose with lower efficiency .
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The expected taxonomic range for this enzyme is: Bacteria, Archaea
Synonyms
KanE, KanM2, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
UDP-alpha-D-kanosamine + 2'-deamino-2'-hydroxyneamine = UDP + kanamycin A
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UDP-alpha-D-kanosamine + 2'-deamino-2'-hydroxyparomamine = UDP + kanamycin X
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UDP-alpha-D-kanosamine + neamine = UDP + kanamycin B
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UDP-alpha-D-kanosamine + paromamine = UDP + kanamycin C
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