The enzyme, characterized from the bacterium Streptomyces thioluteus, participates in the biosynthesis of the antibiotic aureothin. An orthologous enzyme in the bacteria Streptomyces orinoci and Streptomyces spectabilis catalyses a similar reaction in the biosynthesis of spectinabilin.
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The expected taxonomic range for this enzyme is: Streptomyces thioluteus
The enzyme, characterized from the bacterium Streptomyces thioluteus, participates in the biosynthesis of the antibiotic aureothin. An orthologous enzyme in the bacteria Streptomyces orinoci and Streptomyces spectabilis catalyses a similar reaction in the biosynthesis of spectinabilin.
in aureothin biosynthesis, methyltransferase AurI transfers the SAM methyl onto the alpha-hydroxyl group of the pyrone ring of demethylluteothin i.e. nordeoxyaureothin, to yield luteothin, i.e. deoxyaureothin
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Enzyme Nomenclature
2.1.1.353 demethylluteothin O-methyltransferase
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