Information on EC 2.7.1.82 - ethanolamine kinase

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The expected taxonomic range for this enzyme is: Bacteria, Eukaryota

EC NUMBER
COMMENTARY
2.7.1.82
-
RECOMMENDED NAME
GeneOntology No.
ethanolamine kinase
REACTION TYPE
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
LITERATURE
phopho group transfer
Q8IIB7
-
phospho group transfer
-
-
-
-
PATHWAY
KEGG Link
MetaCyc Link
choline biosynthesis I
-
Glycerophospholipid metabolism
-
Metabolic pathways
-
phosphatidylethanolamine biosynthesis II
-
SYSTEMATIC NAME
IUBMB Comments
ATP:ethanolamine O-phosphotransferase
-
SYNONYMS
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
LITERATURE
EKI
-
-
-
-
EKI1
-
-
-
-
ethanolamine kinase
Q8IIB7
-
ethanolamine kinase 2
-
-
ethanolamine phosphokinase
-
-
-
-
EtnK
-
-
-
-
Etnk2
-
-
kinase, ethanolamine (phosphorylating)
-
-
-
-
additional information
-
cf. EC 2.7.1.32; choline kinase and ethanolamine kinase activities are mediated by 2 distinct active sites, possibly on a single protein
additional information
-
cf. EC 2.7.1.32; choline kinase and ethanolamine kinase are 2 distinct enzymes
additional information
-
cf. EC 2.7.1.32; choline kinase and ethanolamine kinase are 2 distinct enzymes
additional information
-
cf. EC 2.7.1.32; choline kinase and ethanolamine kinase are 2 distinct enzymes
additional information
-
cf. EC 2.7.1.32; choline kinase and ethanolamine kinase may not have a common active site in a single enzyme protein
additional information
-
cf. EC 2.7.1.32; ethanolamine kinase II and choline kinase do not use a common active site
CAS REGISTRY NUMBER
COMMENTARY
9075-78-9
-
ORGANISM
COMMENTARY
LITERATURE
SEQUENCE CODE
SEQUENCE DB
SOURCE
NCIB 9205
-
-
Manually annotated by BRENDA team
pigeon
-
-
Manually annotated by BRENDA team
Culex pipiens fatigans
-
-
-
Manually annotated by BRENDA team
Flavobacterium rhenanum
NCIB 9157, enzyme formed only when amino alcohol serves as a substrate and when activated by ADP
-
-
Manually annotated by BRENDA team
chicken
-
-
Manually annotated by BRENDA team
Hemidactylus sp.
lizard
-
-
Manually annotated by BRENDA team
-
SwissProt
Manually annotated by BRENDA team
NCIB 8185, enzyme formed only when amino alcohol serves as a substrate and when activated by ADP
-
-
Manually annotated by BRENDA team
alpha isoform, liver, inducible by CCl4
-
-
Manually annotated by BRENDA team
Ehrlich ascites cells
-
-
Manually annotated by BRENDA team
isozyme alpha, exon 1; isozyme alpha, exon 2; isozyme alpha, exon 3; isozyme alpha, exons 4-8; isozyme alpha, exons 9-11
GenBank
Manually annotated by BRENDA team
isozyme alpha, exon 2'
GenBank
Manually annotated by BRENDA team
isozyme beta
SwissProt
Manually annotated by BRENDA team
isoform EK1
UniProt
Manually annotated by BRENDA team
isoform EK2, bifunctional choline kinase/ethanolamine kinase
UniProt
Manually annotated by BRENDA team
ACTIVATING COMPOUND
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
LITERATURE
IMAGE
2-mercaptoethanol
Culex pipiens fatigans
-
stimulates
cysteine
Culex pipiens fatigans
-
stimulates
EGTA
-
stimulation at 0.4-0.9 mM, inhibition at 1.8 mM
glutathione
Culex pipiens fatigans
-
stimulates
Ki VALUE [mM]
Ki VALUE [mM] Maximum
INHIBITOR
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
LITERATURE
IMAGE
0.73
-
3,3'-dodecane-1,12-diylbis[5-(2-hydroxyethyl)-4-methyl-1,3-thiazol-3-ium]
Q8IIB7
-
TEMPERATURE STABILITY
TEMPERATURE STABILITY MAXIMUM
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
LITERATURE
60
-
Culex pipiens fatigans
-
20 min, complete inactivation
GENERAL STABILITY
ORGANISM
UNIPROT ACCESSION NO.
LITERATURE
inactivation by repeated freezing and thawing
Culex pipiens fatigans
-
EXPRESSION
ORGANISM
UNIPROT ACCESSION NO.
LITERATURE
expression levels increases during erythrocytic development
Q8IIB7