Reference on EC 1.5.3.16 - spermine oxidase and Organism(s) Homo sapiens
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AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Wang, Y.; Devereux, W.; Woster, P.M.; Stewart, T.M.; Hacker, A.; Casero, R.A., Jr.
Cloning and characterization of a human polyamine oxidase that is inducible by polyamine analogue exposure
Cancer Res.
61
5370-5373
2001
Homo sapiens (Q9NWM0)
Wang, Y.; Murray-Stewart, T.; Devereux, W.; Hacker, A.; Frydman, B.; Woster, P.M.; Casero, R.A.Jr.
Properties of purified human polyamine oxidase, PAOh1/SMO
Biochem. Biophys. Res. Commun.
304
605-611
2003
Homo sapiens (Q9NWM0), Homo sapiens
Vujcic, S.; Diegelman, P.; Bacchi, C.J.; Kramer, D.L.; Porter, C.W.
Identification and characterization of a novel flavin-containing spermine oxidase of mammalian cell origin
Biochem. J.
367
665-675
2002
Homo sapiens (Q9NWM0), Homo sapiens, Mus musculus (Q99K82), Mus musculus
Wang, Y.; Hacker, A.; Murray-Stewart, T.; Fleischer, J.G.; Woster, P.M.
Induction of human spermine oxidase SMO(PAOh1) is regulated at the levels of new mRNA synthesis, mRNA stabilization and newly synthesized protein
Biochem. J.
386
543-547
2005
Homo sapiens
Babbar, N.; Casero, R.A.
Tumor necrosis factor-alpha increases reactive oxygen species by inducing spermine oxidase in human lung epithelial cells: a potential mechanism for inflammation-induced carcinogenesis
Cancer Res.
66
11125-11130
2006
Homo sapiens
Murray-Stewart, T.; Wang, Y.; Goodwin, A.; Hacker A.; Meeker, A.; casero, R.A.
Nuclear localization of human spermine oxidase isoforms - possible implications in drug response and disease etiology
FEBS J.
275
2795-2806
2008
Homo sapiens, Homo sapiens (Q9NWM0)
Pledgie, A.; Huang, Y.; Hacker, A.; Zhang, Z.; Woster, P.M.; Davidson, N.E.; Casero, R.A.
Spermine oxidase SMO(PAOh1), not N1-acetylpolyamine oxidase PAO, is the primary source of cytotoxic H2O2 in polyamine analogue-treated human breast cancer cell lines
J. Biol. Chem.
280
39843-39851
2005
Homo sapiens
Järvinen, A.; Grigorenko, N.; Khomutov, A.R.; Hyvönen, M.T.; Uimari, A.; Vepsäläinen, J.; Sinervirta, R.; Keinänen, T.A.; Vujcic, S.; Alhonen, L.; Porter, C.W.; Jänne, J.
Metabolic stability of alpha-methylated polyamine derivatives and their use as substitutes for the natural polyamines.
J. Biol. Chem.
280
6595-6601
2005
Homo sapiens
Goodwin, A.C.; Jadallah, S.; Toubaji, A.; Lecksell, K.; Hicks, J.L.; Kowalski, J.; Bova, G.S.; de Marzo, A.M.; Netto, G.J.; Casero, R.A.
Increased spermine oxidase expression in human prostate cancer and prostatic intraepithelial neoplasia tissues
Prostate
68
766-772
2008
Homo sapiens
Adachi, M.S.; Juarez, P.R.; Fitzpatrick, P.F.
Mechanistic studies of human spermine oxidase: kinetic mechanism and pH effects
Biochemistry
49
386-392
2010
Homo sapiens
Cervelli, M.; Bellavia, G.; Fratini, E.; Amendola, R.; Polticelli, F.; Barba, M.; Federico, R.; Signore, F.; Gucciardo, G.; Grillo, R.; Woster, P.; Casero Jr, R.; Mariottini, P.
Spermine oxidase (SMO) activity in breast tumor tissues and biochemical analysis of the anticancer spermine analogues BENSpm and CPENSpm
BMC Cancer
10
555
2010
Homo sapiens, Mus musculus
Fiori, L.M.; Turecki, G.
Genetic and epigenetic influences on expression of spermine synthase and spermine oxidase in suicide completers
Int. J. Neuropsychopharmacol.
13
725-736
2010
Homo sapiens
Stanic, I.; Facchini, A.; Borzi, R.; Stefanelli, C.; Flamigni, F.
The polyamine analogue N1,N11-diethylnorspermine can induce chondrocyte apoptosis independently of its ability to alter metabolism and levels of natural polyamines
J. Cell. Physiol.
219
109-116
2009
Homo sapiens
Häkkinen, M.; Hyönen, M.; Auriola, S.; Casero Jr., R.; Vepsäläinen, J.; Khomutov, A.; Alhonen, L.; Keinänen, T.
Metabolism of N-alkylated spermine analogues by polyamine and spermine oxidases
Amino Acids
38
369-381
2010
Homo sapiens
Cervelli, M.; Amendola, R.; Polticelli, F.; Mariottini, P.
Spermine oxidase: ten years after
Amino Acids
42
441-450
2012
Homo sapiens, Mus musculus
Moriya, S.; Iwasaki, K.; Samejima, K.; Takao, K.; Kohda, K.; Hiramatsu, K.; Kawakita, M.
A mass spectrometric method to determine activities of enzymes involved in polyamine catabolism
Anal. Chim. Acta
748
45-52
2012
Homo sapiens
Takao, K.; Shirahata, A.; Samejima, K.; Casero, R.A.; Igarashi, K.; Sugita, Y.
Pentamines as substrate for human spermine oxidase
Biol. Pharm. Bull.
36
407-411
2013
Homo sapiens
Capone, C.; Cervelli, M.; Angelucci, E.; Colasanti, M.; Macone, A.; Mariottini, P.; Persichini, T.
A role for spermine oxidase as a mediator of reactive oxygen species production in HIV-Tat-induced neuronal toxicity
Free Radic. Biol. Med.
63
99-107
2013
Homo sapiens
Hong, S.K.; Chaturvedi, R.; Piazuelo, M.B.; Coburn, L.A.; Williams, C.S.; Delgado, A.G.; Casero, R.A.; Schwartz, D.A.; Wilson, K.T.
Increased expression and cellular localization of spermine oxidase in ulcerative colitis and relationship to disease activity
Inflamm. Bowel Dis.
16
1557-1566
2010
Homo sapiens
Cervelli, M.; Salvi, D.; Polticelli, F.; Amendola, R.; Mariottini, P.
in the evolutionary framework of spermine oxidase
J. Mol. Evol.
76
365-370
2013
Homo sapiens, vertebrata, Mus musculus (Q99K82)
Chaturvedi, R.; Asim, M.; Barry, D.P.; Frye, J.W.; Casero, R.A.; Wilson, K.T.
Spermine oxidase is a regulator of macrophage host response to Helicobacter pylori enhancement of antimicrobial nitric oxide generation by depletion of spermine
Amino Acids
46
531-542
2014
Homo sapiens (Q9NWM0), Homo sapiens, Mus musculus (Q99K82), Mus musculus
Moriya, S.S.; Miura, T.; Takao, K.; Sugita, Y.; Samejima, K.; Hiramatsu, K.; Kawakita, M.
Development of irreversible inactivators of spermine oxidase and N1-acetylpolyamine oxidase
Biol. Pharm. Bull.
37
475-480
2014
Homo sapiens (Q9NWM0), Homo sapiens
Leonetti, A.; Cervoni, L.; Polticelli, F.; Kanamori, Y.; Yurtsever, Z.N.; Agostinelli, E.; Mariottini, P.; Stano, P.; Cervelli, M.
Spectroscopic and calorimetric characterization of spermine oxidase and its association forms
Biochem. J.
474
4253-4268
2017
Homo sapiens (Q9NWM0), Homo sapiens
Hu, T.; Sun, D.; Zhang, J.; Xue, R.; Janssen, H.L.A.; Tang, W.; Dong, L.
Spermine oxidase is upregulated and promotes tumor growth in hepatocellular carcinoma
Hepatol. Res.
48
967-977
2018
Homo sapiens (Q9NWM0), Homo sapiens
Sun, L.; Yang, J.; Qin, Y.; Wang, Y.; Wu, H.; Zhou, Y.; Cao, C.
Discovery and antitumor evaluation of novel inhibitors of spermine oxidase
J. Enzyme Inhib. Med. Chem.
34
1140-1151
2019
Homo sapiens (Q9NWM0)
