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2.7.1.25: adenylyl-sulfate kinase

This is an abbreviated version!
For detailed information about adenylyl-sulfate kinase, go to the full flat file.

Word Map on EC 2.7.1.25

Reaction

ATP
+
adenylyl sulfate
=
ADP
 +
3'-phosphoadenylyl sulfate

Synonyms

3'-phosphoadenosine 5'-phosphosulfate synthetase1, 3'-phosphoadenosine-5'-phosphosulfate synthetase, 5'-phosphoadenosine sulfate kinase, adenosine 5'-phosphosulfate kinase, adenosine 5'-phosphosulphate kinase, adenosine 5-phosphosulfate kinase, adenosine 5’-phosphosulfate kinase, adenosine phosphosulfate kinase, adenosine phosphosulfokinase, adenosine-5'-phosphosulfate 3'-phosphotransferase, adenosine-5'-phosphosulfate kinase, adenosine-5'-phosphosulfate-3'-phosphokinase, adenosine-5'phosphosulfate kinase, adenosine-5’-phosphosulfate kinase, adenylyl-sulfate kinase, adenylylsulfate 3'-phosphotransferase, adenylylsulfate kinase, adenylylsulphate kinase, APK, APK1, APK2, APK3, APK4, APS kinase, APS-kinase, APSK, APSK1, ATP adenosine-5'-phosphosulfate 3'-phosphotransferase, ATP sulfurylase-APS kinase, CysC, EhAPSK, EHI_179080, kinase, adenylylsulfate (phosphorylating), MgATP:APS 3'-phosphotransferase, More, MXAN3487, MXAN_3487, MXAN_RS16905, PAPS 2, PAPS synthase, PAPS synthetase, PAPSS, PAPSS 1, PAPSS1

ECTree

     2 Transferases
         2.7 Transferring phosphorus-containing groups
             2.7.1 Phosphotransferases with an alcohol group as acceptor
                2.7.1.25 adenylyl-sulfate kinase

IC50 Value

IC50 Value on EC 2.7.1.25 - adenylyl-sulfate kinase

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IC50 VALUE [mM]
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.00675
1-phenyl-N-[4-(pyridin-2-yl)-1,3-thiazol-2-yl]-1H-imidazole-5-carboxamide
Entamoeba histolytica
pH 8.0, 37°C, recombinant enzyme
0.0063
2-(3-fluorophenoxy)-N-[4-(pyridin-2-yl)-1,3-thiazol-2-yl]acetamide
Entamoeba histolytica
pH 8.0, 37°C, recombinant enzyme
0.00427
2-cycloheptyl-4-(4-methoxy-3-[4-[4-(2H-tetrazol-5-yl)phenoxy]butoxy]phenyl)-4a,5,8,8a-tetrahydrophthalazin-1(2H)-one
Entamoeba histolytica
pH 8.0, 37°C, recombinant enzyme
0.00473
2-cycloheptyl-5-(4-methoxy-3-[4-[4-(2H-tetrazol-5-yl)phenoxy]butoxy]phenyl)-4,4-dimethyl-2,4-dihydro-3H-pyrazol-3-one
Entamoeba histolytica
pH 8.0, 37°C, recombinant enzyme
0.00867
3-(methanesulfonyl)-5,7-dimethyl[1,2]thiazolo[3,4-d]pyrimidine-4,6(5H,7H)-dione
Entamoeba histolytica
pH 8.0, 37°C, recombinant enzyme
0.00573
3-[5-(3,5-dichloro-4-fluorophenyl)-5-(trifluoromethyl)-4,5-dihydro-1,2-oxazol-3-yl]-N-[(1-hydroxy-3,3-dimethyl-1,3-dihydro-2,1-benzoxaborol-5-yl)methyl]-5-methylbenzamide
Entamoeba histolytica
pH 8.0, 37°C, recombinant enzyme
0.00767
3-[7-(benzyloxy)-4,8-dimethyl-2-oxo-2H-1-benzopyran-3-yl]propanoic acid
Entamoeba histolytica
pH 8.0, 37°C, recombinant enzyme
0.01
4-(3-methoxyphenyl)-5-(phenylmethanesulfonyl)-1H-tetrazol-4-ium
Entamoeba histolytica
above, pH 8.0, 37°C, recombinant enzyme
0.01
5-bromo-2-chloro-N-(5-sulfanyl-1,3,4-thiadiazol-2-yl)benzamide
Entamoeba histolytica
above, pH 8.0, 37°C, recombinant enzyme
0.00052
8-(4-methyl-3-[3-[([2-methyl-5-[(4,6,8-trisulfonaphthalen-1-yl)carbamoyl]phenyl]carbamoyl)amino]benzamido]benzamido)naphthalene-1,3,5-trisulfonic acid
Entamoeba histolytica
pH 8.0, 37°C, recombinant enzyme
0.00138
auranofin
Entamoeba histolytica
pH 8.0, 37°C, recombinant enzyme
0.01
delamanid
Entamoeba histolytica
above, pH 8.0, 37°C, recombinant enzyme
0.00047
N,N'-[furan-2,5-diylbis(2-chloro-4,1-phenylene)]diguanidine
Entamoeba histolytica
pH 8.0, 37°C, recombinant enzyme
0.00203
N,N'-[furan-2,5-diylbis(3-chloro-4,1-phenylene)]diguanidine
Entamoeba histolytica
pH 8.0, 37°C, recombinant enzyme
0.00657
N-[2-(5-chloro-2-methoxyanilino)-2-oxoethyl]-N-methyl-2-phenyl-2H-1,2,3-triazole-4-carboxamide
Entamoeba histolytica
pH 8.0, 37°C, recombinant enzyme
15.7 - 17
sulfate