1.1.1.298: 3-hydroxypropionate dehydrogenase (NADP+)
This is an abbreviated version!
For detailed information about 3-hydroxypropionate dehydrogenase (NADP+), go to the full flat file.
Word Map on EC 1.1.1.298
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1.1.1.298
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acetyl-coa
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aurantiacus
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carboxylase
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chloroflexus
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autotrophic
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metallosphaera
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3-hydroxypropionate/4-hydroxybutyrate
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sedula
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malonyl-coenzyme
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acetyl-coenzyme
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succinyl-coa
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propionyl-coa
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acrylic
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value-added
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synthesis
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transhydrogenase
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sulfolobales
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reductase-dependent
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crenarchaeota
- 1.1.1.298
- acetyl-coa
- aurantiacus
- carboxylase
- chloroflexus
-
autotrophic
- metallosphaera
-
3-hydroxypropionate/4-hydroxybutyrate
- sedula
-
malonyl-coenzyme
-
acetyl-coenzyme
- succinyl-coa
- propionyl-coa
-
acrylic
-
value-added
- synthesis
-
transhydrogenase
- sulfolobales
-
reductase-dependent
- crenarchaeota
Reaction
Synonyms
3-HIBADH, 3-hydroxyisobutyrate dehydrogenase, 3-hydroxypropionate dehydrogenase, bi-functional malonyl-CoA reductase, malonate semialdehyde reductase, malonate semialdehyde reductase (NADPH), malonic semialdehyde reductase, malonyl-CoA reductase, MCR, More, MSAR, Msed_1993
ECTree
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Systematic Name
Systematic Name on EC 1.1.1.298 - 3-hydroxypropionate dehydrogenase (NADP+)
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3-hydroxypropionate:NADP+ oxidoreductase
Catalyses the reduction of malonate semialdehyde to 3-hydroxypropanoate, a key step in the 3-hydroxypropanoate and the 3-hydroxypropanoate/4-hydroxybutanoate cycles, autotrophic CO2 fixation pathways found in some green non-sulfur phototrophic bacteria and archaea, respectively [1,2]. The enzyme from Chloroflexus aurantiacus is bifunctional, and also catalyses the upstream reaction in the pathway, EC 1.2.1.75 [3]. Different from EC 1.1.1.59 [3-hydroxypropionate dehydrogenase (NAD+)] by cofactor preference.