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EC Number	Disease	PubMed ID	Title of Publication	Category	Confidence Level
3.4.22.B71	Atherosclerosis	23381569	De-SUMOylation Enzyme of Sentrin/SUMO-Specific Protease 2 Regulates Disturbed Flow-Induced SUMOylation of ERK5 and p53 that Leads to Endothelial Dysfunction and Atherosclerosis.	causal interaction unassigned	2 0
3.4.22.B71	Seizures	25189211	Hyper-SUMOylation of the Kv7 potassium channel diminishes the M-current leading to seizures and sudden death.	causal interaction ongoing research unassigned	3 1 0

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Release 2023.1 (January 2023)