EC Number |
Expression |
Reference |
---|
1.2.1.12 | down |
GAPDH-small interfering RNA knockdown sensitizes the cells to methyl methane sulfonate and bleomycin, which generate lesions that are repaired by APE1, but cells show normal sensitivity to 254-nm UV. GAPDH knockdown cells exhibit an increased level of spontaneous abasic sites in the genomic DNA as a result of diminished APE1 endonuclease activity |
698825 |
1.2.1.12 | more |
72 h cadmium treatment has no stimulating effect on the extractable NADH-specific glyceraldehyde-3-phosphate dehydrogenase activity of whole seedlings |
726233 |
1.2.1.12 | more |
isoform GAPC-1, expression is strong and ubiquitous, insensitive to dark treatments, and unaffected by sucrose |
656414 |
1.2.1.12 | more |
isoform GAPCp-1, expression is ubiquitous, but at lower level than expression of cytosolic isoform GAPC-1. Expression in leaf slowly decreases in the dark and is stable in sucrose-treated leaves |
656414 |
1.2.1.12 | more |
six stress-response elements were found in the upstream region of the CgGAP gene |
-, 741472 |
1.2.1.12 | more |
transcription of GAPDH1 is affected by neither bacterial like Escherichia coli, Edwardsiella tarda, Vibrio anguillarum or Streptococcus iniae nor viral such as rockbream iridovirus, RBIV challenges |
698019 |
1.2.1.12 | up |
24 h after irradiation at 5 gray, nuclear GAPDH levels increase 2.6fold, whereas total GAPDH increases only 1.2fold. Knockdown of GAPDH by siRNA leads to sensitization to X-ray-induced cell death |
696824 |
1.2.1.12 | up |
cadmium induces isoform GAPC1 accumulation in an inactive form. L-buthionine-sulfoximine induces both isoform GAPC1 promoter activity and protein accumulation in the seedling root tips |
726233 |
1.2.1.12 | up |
GAPDH transcript levels are greatly increased by H2O2 treatment |
700672 |
1.2.1.12 | up |
heat (45°C) and cold (10°C) treatments for 6 h increase the expression level of GAPDH gene approximately 6fold, whereas ethanol (6% (v/v)) and salt (1 M) treatments for 6 h increase the expression of the GAPDH gene about 3fold, as compared to the control condition |
-, 710790 |