EC Number   |
Natural Substrates |
|---|
   3.4.23.B10 | Gag polyprotein precursor + H2O |
cleavage into several different mature proteins, processing by the p10 sequence portion of the Gag-polyprotein C-terminus |
| 3.4.23.B10 | Gag polyprotein precursor + H2O |
maturation, processing by the p10-capsid protease sequence of the Gag-polyprotein C-terminus |
| 3.4.23.B10 | gag precursor polyprotein + H2O |
the p2 region of RSV Gag, particularly the Pro-Pro-Pro-Tyr motif is important in the processing of the gag precursor polyprotein, most probably by controlling the activation of the virally encoded protease |
| 3.4.23.B10 | gag precursor polyprotein + H2O |
viral protein maturation occurs after protease subunits are released from the Gag polyprotein |
| 3.4.23.B10 | gag precursor polyprotein + H2O |
cleavage into several different mature proteins, processing by the avian myoblastosis retropepsin, which is part of the Gag-polyprotein and located at the C-terminus |
| 3.4.23.B10 | gag precursor polyprotein + H2O |
cleavage into several different mature proteins, processing by the p15 protein or rous sarcoma virus retropepsin, which is part of the Gag-polyprotein and located at the C-terminus |
| 3.4.23.B10 | Gag-Pol precursor polyprotein + H2O |
cleavage into several different mature proteins |
| 3.4.23.B10 | more |
the enzyme is an intrinsic part of the virus assembly responsible for coordination of the process |
| 3.4.23.B10 | more |
the enzyme is an intrinsic part of the virus assembly responsible for coordination of the process, enzyme inhibition blocks the virus replication |
| 3.4.23.B10 | more |
the enzyme cleaves the RSV Gag protein and virus-like particles (VLPs) |
