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EC Number
Localization
Commentary
GeneOntology No.
Reference
4.1.1.22
acrosome
acrosomes of spermatids and spermatozoa
-
652237
4.1.1.22
cytosol
-
GO:0005829
AmiGO
QuickGO
749421
4.1.1.22
endoplasmic reticulum lumen
the C-terminus is probably required for sorting the enzyme to the endoplasmic reticulum (ER), after which it can be removed to render the active form of the enzyme located in ER lumen
GO:0005788
AmiGO
QuickGO
748845
4.1.1.22
endoplasmic reticulum membrane
N-terminal membrane localization of the precursor 74-kDa form of the enzyme, which has neither an amino terminal signal sequence nor a hydrophobic membrane anchor, but a large C-terminal cytosolic portion, overview
GO:0005789
AmiGO
QuickGO
680148
4.1.1.22
intracellular
-
GO:0005622
AmiGO
QuickGO
665185
4.1.1.22
membrane
-
GO:0016020
AmiGO
QuickGO
4160
4.1.1.22
more
granules of elicited mouse polymorphonuclear leukocytes. Histamine is synthesized by the enzyme attached to the granule membrane of polymorphonuclear leukocytes
-
664842
4.1.1.22
particle-bound
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-
4165
4.1.1.22
soluble
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4160
,
4165
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