EC Number   |
KM Value [mM] |
KM Value Maximum [mM] |
Substrate |
Reference |
|---|
   1.1.1.146 | -999 |
- |
more |
high- and low Km forms, suggesting 2 isoenzymes, high-Km form represents 90% of total activity in untreated microsomes |
285963 |
| 1.1.1.146 | -999 |
- |
more |
substrate specificity and kinetics |
285967 |
| 1.1.1.146 | -999 |
- |
more |
the glucocorticoid and xenobiotic reductase activities show cooperative kinetics |
670264 |
| 1.1.1.146 | 0.0000063 |
- |
NADP+ |
reduction of corticosterone, pH and temperature not specified in the publication |
285951 |
| 1.1.1.146 | 0.0000102 |
- |
NAD+ |
isoform 11beta-HSD2, kidney homogenate |
688766 |
| 1.1.1.146 | 0.000023 |
- |
11beta-hydroxyprogesterone |
isoform 11betaHSD2, pH and temperature not specified in the publication |
761757 |
| 1.1.1.146 | 0.000029 |
- |
7beta,25-dihydroxycholesterol |
recombinant isoform 11beta-HSD1, at pH 7.4 and 37°C |
761758 |
| 1.1.1.146 | 0.000034 |
- |
11beta,21-dihydroxypregn-4-en-3,20-dione |
pH and temperature not specified in the publication |
285951 |
| 1.1.1.146 | 0.000039 |
- |
7-keto,27-hydroxycholesterol |
isoform 11beta-HSD1, at pH 7.4, temperature not specified in the publication |
761665 |
| 1.1.1.146 | 0.000056 |
- |
11beta-hydroxytestosterone |
pH 7.4, 37°C, microsomal assay |
725812 |
