Activating Compound | Comment | Organism | Structure |
---|---|---|---|
phorbol 12-myrisate 13-acetate | - |
Homo sapiens | |
thymic stromal lymphopoietin | stimulates mRNA synthesis | Homo sapiens |
Application | Comment | Organism |
---|---|---|
medicine | dendritic cells in the epidermis and dermis are capable of functioning as an important source of PGD2 in the skin, thereby contributing to or regulating innate and/or acquired immune responses of the skin | Homo sapiens |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
26000 | - |
determined by SDS-PAGE and Western Blot analysis | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
Prostaglandin H2 | Homo sapiens | - |
Prostaglandin D2 | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
dendritic cell | - |
Homo sapiens | - |
dermal dendritic cell | - |
Homo sapiens | - |
Langerhans cell | epidermal Langerhans cell | Homo sapiens | - |
myeloid dendritic cell | - |
Homo sapiens | - |
plasmacytoid dendritic cell | - |
Homo sapiens | - |
skin | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
Prostaglandin H2 | - |
Homo sapiens | Prostaglandin D2 | - |
? |
Synonyms | Comment | Organism |
---|---|---|
H-PGDS | - |
Homo sapiens |
Hematopoietic prostaglandin D synthase | - |
Homo sapiens |
Prostaglandin D synthase | - |
Homo sapiens |
Organism | Comment | Expression |
---|---|---|
Homo sapiens | lipopolysaccharide, LPS, reduces H-PGDS expression | down |